Inflammation in stroke: the role of cholinergic, purinergic and glutamatergic signaling

A Martín, M Domercq, C Matute - Therapeutic advances in …, 2018 - journals.sagepub.com
The inflammatory response is a major factor in stroke pathophysiology and contributes to
secondary neuronal damage in both acute and chronic stages of the ischemic injury. Recent …

Therapeutic advances for treating memory impairments in perinatal brain injuries with implications for cerebral palsy: a systematic review and meta-analysis of …

CMS da Silva Calado, R Manhães-de-Castro… - Experimental …, 2023 - Elsevier
Cerebral palsy (CP) is a neurodevelopmental disorder caused by damage to the immature
brain. CP is considered the main cause of physical disability in childhood. Studies have …

Isoquinoline Alkaloid Contents in Macleaya cordata Extracts and Their Acetylcholinesterase and Butyrylcholinesterase Inhibition

T Tuzimski, A Petruczynik, M Szultka-Młyńska… - Molecules, 2022 - mdpi.com
An important strategy for treating neurodegenerative disorders is to maintain the levels of
acetylcholine in the synaptic cleft by blocking the cholinesterases. Searching for new …

Preventive and therapeutic effects of environmental enrichment in Wistar rats submitted to neonatal hypoxia-ischemia

LE Durán-Carabali, DM Arcego, EF Sanches… - Behavioural brain …, 2019 - Elsevier
Environmental enrichment (EE) at early stages of neurodevelopment attenuates HI-induced
behavioral, histological and cellular damage. However, the effects of EE exposure during …

[HTML][HTML] Differential glucose and beta-hydroxybutyrate metabolism confers an intrinsic neuroprotection to the immature brain in a rat model of neonatal hypoxia …

FK Odorcyk, LE Duran-Carabali, DS Rocha… - Experimental …, 2020 - Elsevier
Neonatal hypoxia ischemia (HI) is the main cause of newborn mortality and morbidity.
Preclinical studies have shown that the immature rat brain is more resilient to HI injury …

Maternal environmental enrichment protects neonatal brains from hypoxic-ischemic challenge by mitigating brain energetic dysfunction and modulating glial cell …

LE Durán-Carabali, FK Odorcyk, LK Grun… - Experimental …, 2024 - Elsevier
There is evidence that maternal milieu and changes in environmental factors during the
prenatal period may exert a lasting impact on the brain health of the newborn, even in case …

Impact of peripheral immune cells in experimental neonatal hypoxia-ischemia: A systematic review and meta-analysis

RR Nunes, LE Durán-Carabali, NH Ribeiro… - International …, 2025 - Elsevier
Infiltration of peripheral immune cells into the brain following neonatal hypoxia–ischemia
(HI) contributes to increased neuroinflammation and brain injury. However, the specific roles …

LncRNA TCONS_00041002 improves neurological outcomes in neonatal rats with hypoxic-ischemic encephalopathy by inhibiting apoptosis and promoting neuron …

LL Xiong, LL Xue, RL Du, Y Xu, YJ Niu, Q Hu… - Experimental …, 2021 - Elsevier
It has been reported that Neonatal hypoxic-ischemic encephalopathy (HIE) could induce
apoptosis in neonates and result in cognitive and sensory impairments, which are …

Plinia trunciflora Extract Administration Prevents HI-Induced Oxidative Stress, Inflammatory Response, Behavioral Impairments, and Tissue Damage in Rats

AVS Carvalho, RT Ribeiro, LE Durán-Carabali… - Nutrients, 2022 - mdpi.com
The disruption of redox homeostasis and neuroinflammation are key mechanisms in the
pathogenesis of brain hypoxia–ischemia (HI); medicinal plants have been studied as a …

Production of cholinesterase-inhibiting compounds in in vitro cultures of club mosses

WJ Szypuła, A Pietrosiuk - Plant cell and tissue differentiation and …, 2021 - Springer
This review provides a comprehensive overview of the cholinesterase-inhibiting compound
production in in vitro culture of club mosses (Lycopodiaceae sensu lato). Some hallmarks in …