Antimicrobial peptides: an update on classifications and databases

A Bin Hafeez, X Jiang, PJ Bergen, Y Zhu - International journal of …, 2021 - mdpi.com
Antimicrobial peptides (AMPs) are distributed across all kingdoms of life and are an
indispensable component of host defenses. They consist of predominantly short cationic …

Role of metabolic endotoxemia in systemic inflammation and potential interventions

S Mohammad, C Thiemermann - Frontiers in immunology, 2021 - frontiersin.org
Diet-induced metabolic endotoxemia is an important factor in the development of many
chronic diseases in animals and man. The gut epithelium is an efficient barrier that prevents …

Antimicrobial peptides, conventional antibiotics, and their synergistic utility for the treatment of drug‐resistant infections

Y Zhu, W Hao, X Wang, J Ouyang… - Medicinal Research …, 2022 - Wiley Online Library
Antimicrobial peptides (AMPs), also known as host defense peptides (HDPs), are important
effector immune defense molecules in multicellular organisms. AMPs exert their …

The demand for new antibiotics: antimicrobial peptides, nanoparticles, and combinatorial therapies as future strategies in antibacterial agent design

A León-Buitimea, CR Garza-Cárdenas… - Frontiers in …, 2020 - frontiersin.org
The inappropriate use of antibiotics and an inadequate control of infections have led to the
emergence of resistant strains which represent a major threat to public health and the global …

Advances in antimicrobial microneedle patches for combating infections

R Jamaledin, CKY Yiu, EN Zare, LN Niu… - Advanced …, 2020 - Wiley Online Library
Skin infections caused by bacteria, viruses and fungi are difficult to treat by conventional
topical administration because of poor drug penetration across the stratum corneum. This …

[HTML][HTML] Design strategies for adhesive hydrogels with natural antibacterial agents as wound dressings: Status and trends

H Yao, M Wu, L Lin, Z Wu, M Bae, S Park, S Wang… - Materials Today Bio, 2022 - Elsevier
The wound healing process is usually susceptible to different bacterial infections due to the
complex physiological environment, which significantly impairs wound healing. The topical …

Nanomedicine and advanced technologies for burns: Preventing infection and facilitating wound healing

MAM Jahromi, PS Zangabad, SMM Basri… - Advanced drug delivery …, 2018 - Elsevier
According to the latest report from the World Health Organization, an estimated 265,000
deaths still occur every year as a direct result of burn injuries. A widespread range of these …

Antimicrobial peptides (AMPs): Ancient compounds that represent novel weapons in the fight against bacteria

JM Ageitos, A Sánchez-Pérez, P Calo-Mata… - Biochemical …, 2017 - Elsevier
Antimicrobial peptides (AMPs) are short peptidic molecules produced by most living
creatures. They help unicellular organisms to successfully compete for nutrients with other …

The potential of human peptide LL-37 as an antimicrobial and anti-biofilm agent

KE Ridyard, J Overhage - Antibiotics, 2021 - mdpi.com
The rise in antimicrobial resistant bacteria threatens the current methods utilized to treat
bacterial infections. The development of novel therapeutic agents is crucial in avoiding a …

Biofilm-innate immune interface: contribution to chronic wound formation

Z Versey, WS da Cruz Nizer, E Russell, S Zigic… - Frontiers in …, 2021 - frontiersin.org
Delayed wound healing can cause significant issues for immobile and ageing individuals as
well as those living with co-morbid conditions such as diabetes, cardiovascular disease, and …