Beneficial effects of physical exercise on neuroplasticity and cognition

K Hötting, B Röder - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
The human brain adapts to changing demands by altering its functional and structural
properties (“neuroplasticity”) which results in learning and acquiring skills. Convergent …

Exercise as a novel treatment for drug addiction: a neurobiological and stage-dependent hypothesis

WJ Lynch, AB Peterson, V Sanchez, J Abel… - … & Biobehavioral Reviews, 2013 - Elsevier
Physical activity, and specifically exercise, has been suggested as a potential treatment for
drug addiction. In this review, we discuss clinical and preclinical evidence for the efficacy of …

Adult neurogenesis and psychiatric disorders

E Kang, Z Wen, H Song… - Cold Spring Harbor …, 2016 - cshperspectives.cshlp.org
Psychiatric disorders continue to be among the most challenging disorders to diagnose and
treat because there is no single genetic or anatomical locus that is causative for the disease …

Re-evaluating the link between neuropsychiatric disorders and dysregulated adult neurogenesis

S Yun, RP Reynolds, I Masiulis, AJ Eisch - Nature medicine, 2016 - nature.com
People diagnosed with neuropsychiatric disorders such as depression, anxiety, addiction or
schizophrenia often have dysregulated memory, mood, pattern separation and/or reward …

Exercise increases mTOR signaling in brain regions involved in cognition and emotional behavior

BA Lloyd, HS Hake, T Ishiwata, CE Farmer… - Behavioural brain …, 2017 - Elsevier
Exercise can enhance learning and memory and produce resistance against stress-related
psychiatric disorders such as depression and anxiety. In rats, these beneficial effects of …

Caudate nucleus volume mediates the link between cardiorespiratory fitness and cognitive flexibility in older adults

TD Verstynen, B Lynch, DL Miller… - Journal of aging …, 2012 - Wiley Online Library
The basal ganglia play a central role in regulating the response selection abilities that are
critical for mental flexibility. In neocortical areas, higher cardiorespiratory fitness levels are …

Does physical activity protect against drug abuse vulnerability?

MT Bardo, WM Compton - Drug and alcohol dependence, 2015 - Elsevier
Background The current review examined recent literature to determine our state of
knowledge about the potential ability of physical activity serve as a protectant against drug …

[HTML][HTML] Intermittent voluntary wheel running promotes resilience to the negative consequences of repeated social defeat in mice

C Calpe-López, MA Martínez-Caballero… - Physiology & …, 2022 - Elsevier
A novel approach to reduce the incidence of substance use disorders is to promote
resilience to stress using environmental resources such as physical exercise. In the present …

Neuroplastic and cognitive impairment in substance use disorders: a therapeutic potential of cognitive stimulation

P Sampedro-Piquero, DL de Guevara-Miranda… - Neuroscience & …, 2019 - Elsevier
Drug addiction is a chronic and relapsing disorder in which repeated drug exposure
compromises brain neuroplasticity. Brain areas normally involved in learning and goal …

The therapeutic potential of exercise for neuropsychiatric diseases: A review

S Swenson, K Blum, T McLaughlin, MS Gold… - Journal of the …, 2020 - Elsevier
Exercise is known to have a myriad of health benefits. There is much to be learned from the
effects of exercise and its potential for prevention, attenuation and treatment of multiple …