A review of cancer genetics and genomics studies in Africa

SO Rotimi, OA Rotimi, B Salhia - Frontiers in oncology, 2021 - frontiersin.org
Cancer is the second leading cause of death globally and is projected to overtake infectious
disease as the leading cause of mortality in Africa within the next two decades. Cancer is a …

Human variability in isoform-specific UDP-glucuronosyltransferases: markers of acute and chronic exposure, polymorphisms and uncertainty factors

EEJ Kasteel, K Darney, NI Kramer, J Dorne… - Archives of …, 2020 - Springer
UDP-glucuronosyltransferases (UGTs) are involved in phase II conjugation reactions of
xenobiotics and differences in their isoform activities result in interindividual kinetic …

Review of prostate cancer genomic studies in Africa

C Samtal, I El Jaddaoui, S Hamdi… - Frontiers in …, 2022 - frontiersin.org
Prostate cancer (PCa) is the second most commonly diagnosed in men worldwide and one
of the most frequent cancers in men in Africa. The heterogeneity of this cancer fosters the …

Properties of Dietary Flavone Glycosides, Aglycones, and Metabolites on the Catalysis of Human Endoplasmic Reticulum Uridine Diphosphate …

T Xu, Y Lv, Y Cui, D Liu, T Xu, B Lu, X Yang - Nutrients, 2023 - mdpi.com
Flavone glycosides, their aglycones, and metabolites are the major phytochemicals in
dietary intake. However, there are still many unknowns about the cellular utilization and …

Towards next generation risk assessment of chemicals: bayesian meta-analysis of human variability in metabolism and transporters and application for the derivation …

K Darney - 2020 - theses.hal.science
In the modern world, humans are exposed to a wide range of chemicals throughout their life.
Human risk assessment of chemicals is of considerable public health importance and …