African trypanosomes are responsible for important diseases of humans and animals in sub-
Saharan Africa. The best-studied species is Trypanosoma brucei, which is characterized by …

An intriguing and remarkable feature of African trypanosomes is their antigenic variation
system, mediated by the variant surface glycoprotein (VSG) family and fundamental to both …

AlphaFold2 and RoseTTAfold represent a transformative advance for predicting protein
structure. They are able to make very high-quality predictions given a high-quality alignment …

Fasciola hepatica infection is responsible for substantial economic losses in livestock
worldwide and poses a threat to human health in endemic areas. The mainstay of control in …

African trypanosomes cause human African trypanosomiasis and animal African
trypanosomiasis. They are transmitted by tsetse flies in sub-Saharan Africa. Although most …

The process of antigenic variation in parasitic African trypanosomes is a remarkable
mechanism for outwitting the immune system of the mammalian host, but it requires a …

Animal African Trypanosomiasis (AAT) is a debilitating livestock disease prevalent across
sub-Saharan Africa, a main cause of which is the protozoan parasite Trypanosoma …

Trypanosoma congolense is a principal agent causing livestock trypanosomiasis in Africa,
costing developing economies billions of dollars and undermining food security. Only the …

A key morphological feature of kinetoplastid parasites is the position and length of flagellum
attachment to the cell body. This lateral attachment is mediated by the flagellum attachment …

Animal African trypanosomiasis (AAT) is a severe, wasting disease of domestic livestock and
diverse wildlife species. The disease in cattle kills millions of animals each year and inflicts a …