Cannabinoids and appetite: food craving and food pleasure

TC Kirkham - International Review of Psychiatry, 2009 - Taylor & Francis
The ability of Cannabis sativa to promote eating has been documented for many centuries,
with the drug reported by its users to promote strong cravings for, and an intensification of …

A systematic review of genetic variants associated with metabolic syndrome in patients with schizophrenia

S Malan-Mueller, S Kilian, LL van den Heuvel… - Schizophrenia …, 2016 - Elsevier
Metabolic syndrome (MetS) is a cluster of factors that increases the risk of cardiovascular
disease (CVD), one of the leading causes of mortality in patients with schizophrenia …

What role does the endocannabinoid system play in the pathogenesis of obesity?

P Schulz, S Hryhorowicz, AM Rychter, A Zawada… - Nutrients, 2021 - mdpi.com
The endocannabinoid system (ECS) is an endogenous signaling system formed by specific
receptors (cannabinoid type 1 and type 2 (CB1 and CB2)), their endogenous ligands …

A common polymorphism in the cannabinoid receptor 1 (CNR1) gene is associated with antipsychotic-induced weight gain in Schizophrenia

AK Tiwari, CC Zai, O Likhodi, A Lisker… - …, 2010 - nature.com
Antipsychotic-induced weight gain has emerged as a serious complication in the treatment
of patients with atypical antipsychotic drugs. The cannabinoid receptor 1 (CNR1) is …

Cannabinoid receptors in brain: pharmacogenetics, neuropharmacology, neurotoxicology, and potential therapeutic applications

ES Onaivi - International review of neurobiology, 2009 - Elsevier
Much progress has been achieved in cannabinoid research. A major breakthrough in
marijuana-cannabinoid research has been the discovery of a previously unknown but …

Genomic insights into early-onset obesity

H Choquet, D Meyre - Genome Medicine, 2010 - Springer
The biological causes of childhood obesity are complex. Environmental factors, such as
massive marketing campaigns for food leading to over-nutrition and snacking and the …

Moderation of antipsychotic-induced weight gain by energy balance gene variants in the RUPP autism network risperidone studies

EL Nurmi, SL Spilman, F Whelan, LL Scahill… - Translational …, 2013 - nature.com
Second-generation antipsychotic exposure, in both children and adults, carries significant
risk for excessive weight gain that varies widely across individuals. We queried common …

On the role of central type-1 cannabinoid receptor gene regulation in food intake and eating behaviors

M Pucci, E Zaplatic, MV Micioni Di Bonaventura… - International Journal of …, 2021 - mdpi.com
Different neuromodulatory systems are involved in long-term energy balance and body
weight and, among these, evidence shows that the endocannabinoid system, in particular …

Pharmacogenetics of the G protein-coupled receptors

MD Thompson, DEC Cole, V Capra… - … in Drug Discovery and …, 2014 - Springer
Pharmacogenetics investigates the influence of genetic variants on physiological
phenotypes related to drug response and disease, while pharmacogenomics takes a …

Genetic polymorphisms of the endocannabinoid system in obesity and diabetes

JM Doris, SA Millar, I Idris… - Diabetes, Obesity and …, 2019 - Wiley Online Library
The endocannabinoid system (ECS) is involved in many physiological processes including
fertility, pain and energy regulation. The aim of this systematic review was to examine the …