Aptamers are short, single-stranded DNA, RNA, or synthetic XNA molecules that can be
developed with high affinity and specificity to interact with any desired targets. They have …

Simple Summary All cells are covered in a thick layer of sugar molecules known as glycans.
Changes to this sugar coat are common in cancer, and in particular cancer cells often …

How disseminated tumour cells engage specific stromal components in distant organs for
survival and outgrowth is a critical but poorly understood step of the metastatic cascade …

Cell surface glycosylation is dynamic and often changes in response to cellular
differentiation under physiological or pathophysiological conditions. Altered glycosylation on …

Aptamer-related technologies represent a revolutionary advancement in the capacity to
rapidly develop new classes of targeting ligands. Structurally distinct RNA and DNA …

Metastasis is a major contributor to cancer-associated deaths. It involves complex
interactions between primary tumorigenic sites and future metastatic sites. Accumulation …

Infectious diseases are considered as a pressing challenge to global public health. Accurate
and rapid diagnostics tools for early recognition of the pathogen, as well as individualized …

Central nervous system metastases have been reported in 15–25% of breast cancer
patients, and the incidence is increasing. Moreover, the survival of these patients is …

Nucleic acid aptamers are short RNA-or DNA-based affinity reagents typically selected from
combinatorial libraries to bind to a specific target such as a protein, a small molecule, whole …

Aptamers, a class of oligonucleotides that can bind with molecular targets with high affinity
and specificity, have been widely applied in research fields including biosensing, imaging …