Maternal nutrition plays a critical role in fetal development and can influence adult onset of
disease. Linoleic acid (LA) and alpha‐linolenic acid (ALA) are major omega‐6 (n‐6) and n …

Intrauterine hypoxia is a feature of pregnancy complications, both at high altitude and sea
level. To understand the placental response to reduced oxygen availability, small animal …

The heterogeneous characteristics of neurodevelopmental disorders (NDDs) have resulted
in varied perspectives on their causation. The biology behind the phenotypic heterogeneity …

Consistent with the paradigm shifting observations of David Barker and colleagues that
revealed a powerful relationship between decreased weight through 2 years of age and …

Oligosaccharides are one of the most important components in mammalian milk. Milk
oligosaccharides can promote colonization of gut microbiota and protect newborns from …

Lactation is a critical period during which maternal nutritional and environmental challenges
affect milk composition and, therefore, organ differentiation, structure, and function in …

Hypertension, the leading cause of death among all cardiovascular disease (CVD) risk
factors, affects> 1.1 billion adults worldwide. 1, 2 Fetal growth restriction (FGR), generally …

Biomarkers for placental dysfunction are currently lacking. We recently identified SPINT1 as
a novel biomarker; SPINT2 is a functionally related placental protease inhibitor. This study …

This study was performed to identify transcriptional alterations in male intrauterine growth
restricted (IUGR) rats during and at the end of nephrogenesis in order to generate …

Perinatal nutrition is a key player in the susceptibility to developing metabolic diseases in
adulthood, leading to the concept of “metabolic programming”. The aim of this study was to …