[HTML][HTML] Cytoreduction for colorectal metastases: liver, lung, peritoneum, lymph nodes, bone, brain. When does it palliate, prolong survival, and potentially cure?

CL Stewart, S Warner, K Ito, M Raoof… - Current problems in …, 2018 - ncbi.nlm.nih.gov
Colorectal cancer commonly metastasizes. The liver is the most frequent site of metastases
and dominates the length of survival for this disease. As surgical and systemic therapies …

The molecular biology of peritoneal metastatic disease

S Bootsma, MF Bijlsma, L Vermeulen - EMBO molecular medicine, 2023 - embopress.org
Peritoneal metastases are a common form of tumor cell dissemination in gastrointestinal
malignancies. Peritoneal metastatic disease (PMD) is associated with severe morbidity and …

Peritoneal metastases from colorectal cancer: defining and addressing the challenges

O Kranenburg, K Speeten, I Hingh - Frontiers in oncology, 2021 - frontiersin.org
The presence of peritoneal metastases (PM) in patients with colorectal cancer (CRC) is
associated with an extremely poor prognosis. The diagnosis of PM is challenging, resulting …

Fibroblast activation protein identifies Consensus Molecular Subtype 4 in colorectal cancer and allows its detection by 68Ga-FAPI-PET imaging

E Strating, E Wassenaar, M Verhagen… - British journal of …, 2022 - nature.com
Background In colorectal cancer (CRC), the consensus molecular subtype 4 (CMS4) is
associated with therapy resistance and poor prognosis. Clinical diagnosis of CMS4 is …

Site of recurrence and survival after surgery for colorectal peritoneal metastasis

E Breuer, M Hebeisen, MA Schneider… - JNCI: Journal of the …, 2021 - academic.oup.com
Background Multimodal treatment, including systemic treatment and surgery, improved the
prognosis of peritoneal metastasis (PM). Despite all efforts, recurrence rates remain high …

Logic gate-driven dual-index balanced visualization strategy for tumor metastasis diagnosis

P Yu, W Chen, L Ge, J Fang, X Huang, H Tong… - Biosensors and …, 2023 - Elsevier
Exfoliated tumor cells are integral to malignant tumors diagnosis. The process of clinical
cytology of exfoliation involves several complex steps that require at least two days of …

Role of Tumor-informed Personalized Circulating Tumor DNA Assay in Informing Recurrence in Patients With Peritoneal Metastases From Colorectal and High-grade …

A Dhiman, V Kothary, HDD Witmer, C Bregio… - Annals of …, 2023 - journals.lww.com
Objective: To investigate the role of a personalized, tumor-informed circulating tumor DNA
(ctDNA) assay in informing recurrence in patients with peritoneal metastases (PM) from …

The multivisceral landscape of colorectal cancer metastasis: implications for targeted therapies

D Wolf, S Salcher, A Pircher - The Journal of Clinical …, 2024 - Am Soc Clin Investig
Colorectal cancer (CRC) is among the most common cancer types and the second deadliest
malignancy for both sexes. Metastatic disease poses substantial therapeutic challenges …

Impact of enhanced recovery after surgery on postoperative outcomes for patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

B White, F Dahdaleh, SA Naffouje, N Kothari… - Annals of Surgical …, 2021 - Springer
Background Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy
(HIPEC) have been associated with significant morbidity and increased hospital length of …

Metastatic Colon Cancer Treatment Using S100A9-Targeted Cowpea Mosaic Virus Nanoparticles

YH Chung, BA Volckaert, NF Steinmetz - Biomacromolecules, 2022 - ACS Publications
Peritoneal metastases (PMs) occur due to the metastasis of gynecological and
gastrointestinal cancers such as ovarian, colon, pancreatic, or gastric tumors. PM outgrowth …