The phosphoethanolamine transferase EptA utilizes phosphatidylethanolamine (PE) in the
bacterial cell membrane to modify the structure of lipopolysaccharide, thereby conferring …

Peptidoglycan polymerases, enterobacterial common antigen polymerases, O-antigen
ligases, and other bacterial polysaccharide polymerases (BP-Pols) are glycosyltransferases …

The cell wall is essential for bacteria to maintain structural rigidity and withstand external
osmotic pressure. In bacteria, the cell wall is composed of peptidoglycan. Lipid II is the basic …

Enterococci exhibit intrinsic resistance to cephalosporins, mediated in part by the class B
penicillin-binding protein (bPBP) Pbp4 that exhibits low reactivity toward cephalosporins …

In this study, two magnetic activity-based protein profiling probes based on cephradine and
amoxicillin were first synthesized that were used to produce the natural penicillin-binding …

Objective. The red rhizome of Angiopteris helferiana has been used widely to treat muscle
fatigue, bone pain, and skin infection in Nepal. However, scientific evidence for its bioactive …

Abstract Penicillin-binding protein 2 (PBP2) plays a key role in the formation of
peptidoglycans in bacterial cell walls by crosslinking glycan chains through transpeptidase …

The peptidoglycan (PG) cell wall is the primary protective layer of bacteria, making the
process of PG synthesis a key antibiotic target. Class A penicillin-binding proteins (aPBPs) …

The emergence of drug-resistant strains exacerbates the global challenge of tuberculosis
caused by Mycobacterium tuberculosis (Mtb). Central to the pathogenicity of Mtb is its …

In evolving to obligate intracellular dependence, Chlamydia trachomatis serovar L2 (Ct), has
eliminated several gene products essential for cell division in most other bacteria, including …