Antimicrobial resistance in Mycobacterium tuberculosis: mechanistic and evolutionary perspectives

SM Gygli, S Borrell, A Trauner… - FEMS microbiology …, 2017 - academic.oup.com
Antibiotic-resistant Mycobacterium tuberculosis strains are threatening progress in
containing the global tuberculosis epidemic. Mycobacterium tuberculosis is intrinsically …

Global prevalence of drug-resistant tuberculosis: a systematic review and meta-analysis

N Salari, AH Kanjoori, A Hosseinian-Far… - Infectious Diseases of …, 2023 - Springer
Background Tuberculosis is a bacterial infectious disease, which affects different parts of a
human body, mainly lungs and can lead to the patient's death. The aim of this study is to …

Whole-genome sequencing of rifampicin-resistant Mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genes

I Comas, S Borrell, A Roetzer, G Rose, B Malla… - Nature …, 2012 - nature.com
Epidemics of drug-resistant bacteria emerge worldwide, even as resistant strains frequently
have reduced fitness compared to their drug-susceptible counterparts. Data from model …

Whole Genome Sequencing Reveals Complex Evolution Patterns of Multidrug-Resistant Mycobacterium tuberculosis Beijing Strains in Patients

M Merker, TA Kohl, A Roetzer, L Truebe, E Richter… - PloS one, 2013 - journals.plos.org
Multidrug-resistant (MDR) Mycobacterium tuberculosis complex (MTBC) strains represent a
major threat for tuberculosis (TB) control. Treatment of MDR-TB patients is long and less …

The burden of tuberculosis in crisis-affected populations: a systematic review

W Kimbrough, V Saliba, M Dahab… - The Lancet infectious …, 2012 - thelancet.com
Crises caused by armed conflict, forced population displacement, or natural disasters result
in high rates of excess morbidity and mortality from infectious diseases. Many of these crises …

Insights into the origin, emergence, and current spread of a successful Russian clone of Mycobacterium tuberculosis

I Mokrousov - Clinical microbiology reviews, 2013 - Am Soc Microbiol
Mycobacterium tuberculosis variant Beijing B0/W148 is regarded as a successful clone of M.
tuberculosis that is widespread in the former Soviet Union and respective immigrant …

Genomic Diversity among Drug Sensitive and Multidrug Resistant Isolates of Mycobacterium tuberculosis with Identical DNA Fingerprints

S Niemann, CU Köser, S Gagneux, C Plinke… - PloS one, 2009 - journals.plos.org
Background Mycobacterium tuberculosis complex (MTBC), the causative agent of
tuberculosis (TB), is characterized by low sequence diversity making this bacterium one of …

Mycobacterium tuberculosis Beijing Lineage Favors the Spread of Multidrug-Resistant Tuberculosis in the Republic of Georgia

S Niemann, R Diel, G Khechinashvili… - Journal of clinical …, 2010 - Am Soc Microbiol
High rates and transmission of multidrug-resistant (MDR) tuberculosis (TB) have been
associated with the Mycobacterium tuberculosis complex (MTBC) Beijing lineage, pointing …

Molecular epidemiology and transmission dynamics of Mycobacterium tuberculosis in Northwest Ethiopia: new phylogenetic lineages found in Northwest Ethiopia

B Tessema, J Beer, M Merker, F Emmrich, U Sack… - BMC infectious …, 2013 - Springer
Abstract Background Although Ethiopia ranks seventh among the world's 22 high-burden
tuberculosis (TB) countries, little is known about strain diversity and transmission. In this …

Diversity and evolution of Mycobacterium tuberculosis: moving to whole-genome-based approaches

S Niemann, P Supply - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
Genotyping of clinical Mycobacterium tuberculosis complex (MTBC) strains has become a
standard tool for epidemiological tracing and for the investigation of the local and global …