Epithelial–mesenchymal transition (EMT) is an essential process in normal embryonic
development and tissue regeneration. However, aberrant reactivation of EMT is associated …

The transdifferentiation of epithelial cells into motile mesenchymal cells, a process known as
epithelial–mesenchymal transition (EMT), is integral in development, wound healing and …

During organogenesis, epithelial cells can give rise to mesenchymal cells through epithelial–
mesenchymal transition. The reverse process, mesenchymal–epithelial transition (MET), can …

Epithelial cells require apical–basal plasma membrane polarity to carry out crucial vectorial
transport functions and cytoplasmic polarity to generate different cell progenies for tissue …

Epithelial-mesenchymal transition (EMT) is a crucial, evolutionarily conserved process that
occurs during development and is essential for shaping embryos. Also implicated in cancer …

After years of extensive scientific discovery much has been learned about the networks that
regulate epithelial homeostasis. Loss of expression or functional activity of cell adhesion …

Background In preimplantation mouse embryos, the first cell fate specification to the
trophectoderm or inner cell mass occurs by the early blastocyst stage. The cell fate is …

During evolution from primitive species, a mechanism, termed epithelial-mesenchymal
transition (EMT), was established to create mesenchymal cells from a pre-existing epithelial …

Cells exhibit morphological and molecular asymmetries that are broadly categorized as cell
polarity. The cell polarity established in early embryos prefigures the macroscopic …

The structure and function of the barrier layers restricting the free diffusion of substances
between the central nervous system (brain and spinal cord) and the systemic circulation is of …