Defining the role of natural killer cells in COVID-19
Natural killer (NK) cells are critical effectors of antiviral immunity. Researchers have
therefore sought to characterize the NK cell response to coronavirus disease 2019 (COVID …
therefore sought to characterize the NK cell response to coronavirus disease 2019 (COVID …
Understanding NK cell biology for harnessing NK cell therapies: targeting cancer and beyond
E Shin, SH Bak, T Park, JW Kim, SR Yoon… - Frontiers in …, 2023 - frontiersin.org
Gene-engineered immune cell therapies have partially transformed cancer treatment, as
exemplified by the use of chimeric antigen receptor (CAR)-T cells in certain hematologic …
exemplified by the use of chimeric antigen receptor (CAR)-T cells in certain hematologic …
Production of MHCII‐expressing classical monocytes increases during aging in mice and humans
Aging is associated with increased monocyte production and altered monocyte function.
Classical monocytes are heterogenous and a shift in their subset composition may underlie …
Classical monocytes are heterogenous and a shift in their subset composition may underlie …
Mechanistic insights into the immune pathophysiology of COVID-19; an in-depth review
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which causes
coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In …
coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In …
[HTML][HTML] Mild/asymptomatic COVID-19 in unvaccinated pregnant mothers impairs neonatal immune responses
Maternal SARS-CoV-2 infection triggers placental inflammation and alters cord blood
immune cell composition. However, most studies focus on outcomes of severe maternal …
immune cell composition. However, most studies focus on outcomes of severe maternal …
SARS-CoV-2 infection establishes a stable and age-independent CD8+ T cell response against a dominant nucleocapsid epitope using restricted T cell receptors
The resolution of SARS-CoV-2 replication hinges on cell-mediated immunity, wherein CD8+
T cells play a vital role. Nonetheless, the characterization of the specificity and TCR …
T cells play a vital role. Nonetheless, the characterization of the specificity and TCR …
Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology
Age is a major risk factor for severe coronavirus disease 2019 (COVID-19), yet the
mechanisms behind this relationship have remained incompletely understood. To address …
mechanisms behind this relationship have remained incompletely understood. To address …
Pathogenesis of pulmonary long COVID-19
AC Borczuk - Modern Pathology, 2024 - Elsevier
COVID-19 is characterized by an acute respiratory illness that, in some patients, progresses
to respiratory failure, largely demonstrating a pattern of acute respiratory distress syndrome …
to respiratory failure, largely demonstrating a pattern of acute respiratory distress syndrome …
Age-dependent NK cell dysfunctions in severe COVID-19 patients
Natural Killer (NK) cells are key innate effectors of antiviral immune response, and their
activity changes in ageing and severe acute respiratory syndrome coronavirus 2 (SARS …
activity changes in ageing and severe acute respiratory syndrome coronavirus 2 (SARS …
Obesity correlates with pronounced aberrant innate immune responses in hospitalized aged COVID-19 patients
MZ Zulu, S Sureshchandra, AN Pinski, B Doratt… - Frontiers in …, 2021 - frontiersin.org
Both age and obesity are leading risk factors for severe coronavirus disease 2019 (COVID-
19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …