Functional comparison of neurotransmitter receptor subtypes in mammalian central nervous system

RA Nicoll, RC Malenka, JA Kauer - Physiological reviews, 1990 - journals.physiology.org
Communication between nerve cells in the central nervous system (CNS) occurs at
synapses, which are specialized sites between the presynaptic nerve terminal and the …

[HTML][HTML] Synaptic and extrasynaptic NMDA receptors are gated by different endogenous coagonists

T Papouin, L Ladépêche, J Ruel, S Sacchi… - Cell, 2012 - cell.com
N-methyl-d-aspartate receptors (NMDARs) are located in neuronal cell membranes at
synaptic and extrasynaptic locations, where they are believed to mediate distinct …

High-affinity zinc inhibition of NMDA NR1–NR2A receptors

P Paoletti, P Ascher, J Neyton - Journal of Neuroscience, 1997 - Soc Neuroscience
Micromolar concentrations of extracellular Zn2+ are known to antagonize native NMDA
receptors via a dual mechanism involving both a voltage-independent and a voltage …

Contribution of astrocytes to hippocampal long-term potentiation through release of d-serine

Y Yang, W Ge, Y Chen, Z Zhang… - Proceedings of the …, 2003 - National Acad Sciences
Repetitive correlated activation of pre-and postsynaptic neurons induced long-term
potentiation (LTP) of synaptic transmission among hippocampal neurons grown on a layer of …

NMDA receptors: linking physiological output to biophysical operation

GJ Iacobucci, GK Popescu - Nature Reviews Neuroscience, 2017 - nature.com
NMDA receptors are preeminent neurotransmitter-gated channels in the CNS, which
respond to glutamate in a manner that integrates multiple external and internal cues. They …

Presynaptic mechanism for long-term potentiation in the hippocampus

JM Bekkers, CF Stevens - Nature, 1990 - nature.com
potentiation in the hippocampus Page 1 ARTICLES Presynaptic mechanism for long-term
potentiation in the hippocampus John M., Bekkers & Charles F, Stevens The Salk Institute …

Zinc: the brain's dark horse

BKY Bitanihirwe, MG Cunningham - Synapse, 2009 - Wiley Online Library
Zinc is a life‐sustaining trace element, serving structural, catalytic, and regulatory roles in
cellular biology. It is required for normal mammalian brain development and physiology …

Organization, control and function of extrasynaptic NMDA receptors

T Papouin, SHR Oliet - … of the Royal Society B: Biological …, 2014 - royalsocietypublishing.org
N-methyl d-aspartate receptors (NMDARs) exist in different forms owing to multiple
combinations of subunits that can assemble into a functional receptor. In addition, they are …

Modulation of inhibitory and excitatory amino acid receptor ion channels by zinc

TG Smart, X Xie, BJ Krishek - Progress in neurobiology, 1994 - Elsevier
Modulation of inhibitory and excitatory amino acid receptor ion channels by zinc - ScienceDirect
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Kynurenine pathway measurements in Huntington's disease striatum: evidence for reduced formation of kynurenic acid

MF Beal, WR Matson, KJ Swartz… - Journal of …, 1990 - Wiley Online Library
Recent evidence suggests that there may be over‐activation of the N‐methyl‐D‐aspartate
(NMDA) subtype of excitatory amino acid receptors in Huntington's disease (HD) …