Assessment of black cumin (Nigella sativa L.) as a food ingredient and putative therapeutic agent

GA Burdock - Regulatory Toxicology and Pharmacology, 2022 - Elsevier
The whole or ground seeds of the food ingredient Nigella sativa L., known in Western culture
as “black cumin” or “black caraway”, has a three-millennial history of use in Middle-and Far …

The effect of Nigella sativa on the measures of liver and kidney parameters: A systematic review and meta-analysis of randomized-controlled trials

E Razmpoosh, S Safi, N Abdollahi… - Pharmacological …, 2020 - Elsevier
The aim of this systematic review and dose–response meta-analysis was to determine the
effect of Nigella sativa (NS) supplementation on liver and kidney parameters. We searched …

[HTML][HTML] A phase I clinical trial to evaluate the safety of thymoquinone-rich black cumin oil (BlaQmax®) on healthy subjects: Randomized, double-blinded, placebo …

JV Thomas, ME Mohan, P Prabhakaran, B Maliakel… - Toxicology Reports, 2022 - Elsevier
Black cumin or black seed (Nigella sativa L.) is a popular medicinal herb and culinary spice
belonging to Ranunculacea family. Thymoquinone (TQ) is the major active phytoconstituent …

Screening of Thymoquinone Content in Commercial Nigella sativa Products to Identify a Promising and Safe Study Medication

E Khaikin, S Chrubasik-Hausmann, S Kaya… - Nutrients, 2022 - mdpi.com
(1) Background: Thymoquinone (TQ) is the leading compound accounting for the
pharmacological effects of Nigella sativa seed oil, also known as black seed oil. This study …

The efficacy of black cumin seed (Nigella sativa) oil and hypoglycemic drug combination to reduce HbA1c level in patients with metabolic syndrome risk

PNR Rachman, E Darmawan - IOP Conference Series …, 2017 - iopscience.iop.org
Metabolic syndrome is a conditions caused by metabolic abnormalities include central
obesity, atherogenic dyslipidemia, hypertension, and insulin resistance. HbA1c examination …

[HTML][HTML] Black seeds: potential health benefits

KW Singletary - Nutrition Today, 2022 - journals.lww.com
Black seeds, sometimes called black cumin, are obtained from the spicy medicinal herb
Nigella sativa that is native to a broad region encompassing the eastern Mediterranean …

The potential of Nigella sativa oil on clinical output improvement of diabetic neuropathy

K Anggadiredja, NF Kurniati - Journal of Applied Pharmaceutical …, 2023 - japsonline.com
Diabetic neuropathy is a condition of impaired nerve function due to complications related to
the development of diabetes through various mechanisms. Clinical improvement in diabetic …

Alleviating effects of Nigella sativa supplements on biomarkers of inflammation and oxidative stress: results from an umbrella meta-analysis

L Xinyu, X Yongliang - Prostaglandins & Other Lipid Mediators, 2024 - Elsevier
Several meta-analyses have examined the effect of Nigella Sativa (N. Sativa)
supplementation on inflammatory and oxidative markers, with conflicting results. So, the …

Nigellasativa L. and its bioactive and nutraceutical components in the management of diabetic peripheral neuropathy

SA Khodaie, R Razavi, H Nikkhah, N Namiranian… - …, 2024 - Springer
Diabetes-induced hyperglycemia leads to excessive production of oxygen free radicals,
inflammatory cytokines, and oxidative stress, which initiates diabetic peripheral neuropathy …

[HTML][HTML] Effect of carvacrol on pulmonary function tests, and total and differential white blood cell counts in healthy volunteers: A randomized clinical trial

V Ghorani, M Boskabady… - Avicenna Journal of …, 2019 - ncbi.nlm.nih.gov
Objective: This is the first study to evaluate the effect of carvacrol on pulmonary function tests
(PFT), and total and differential white blood cell (WBC) counts in healthy volunteers …