BACKGROUND: The American Heart Association (AHA), in conjunction with the National
Institutes of Health, annually reports the most up-to-date statistics related to heart disease …

Valvular heart disease (VHD) is a major contributor to loss of physical function, quality of life
and longevity. The epidemiology of VHD varies substantially around the world, with a …

Valvular heart disease is a rapidly growing cause of global cardiovascular morbidity and
mortality with diverse and evolving geographic distribution. The prevalence of rheumatic …

Health professionals are encouraged to take the ESC/EACTS Guidelines fully into account
when exercising their clinical judgment, as well as in the determination and the …

Calcific aortic valve disease (CAVD) is a highly prevalent condition that comprises a disease
continuum, ranging from microscopic changes to profound fibro-calcific leaflet remodelling …

As populations age worldwide, the burden of valvular heart disease has grown
exponentially, and so has the proportion of affected women. Although rheumatic valve …

STUDY QUESTION What is the current burden of polycystic ovary syndrome (PCOS) at the
global, regional, and country-specific levels in 194 countries and territories according to age …

Calcific aortic valve disease (CAVD) is the most common disorder affecting heart valves and
is characterized by thickening, fibrosis and mineralization of the aortic valve leaflets …

Background Immune system dysregulation plays a critical role in aortic valve calcification
(AVC) and metabolic syndrome (MS) pathogenesis. The study aimed to identify pivotal …

Background: Calcific aortic stenosis (CAS) is the most common valvular heart disease in
older adults and has no effective preventive therapies. Genome-wide association studies …