Spinal cord injuries affect nearly five to ten individuals per million every year. Spinal cord
injury causes damage to the nerves, muscles, and the tissue surrounding the spinal cord …

Mesenchymal stem cells (MSCs) are multipotent stromal cells with the ability to self-renew
and multi-directional differentiation potential. Exogenously administered MSCs can migrate …

Arrest of oligodendrocyte (OL) differentiation and remyelination following myelin damage in
multiple sclerosis (MS) is associated with neurodegeneration and clinical worsening. We …

There is vast evidence for the effect of NOD-like receptor protein-3 (NLRP3) inflammasome
on multiple sclerosis (MS) pathogenesis. Clemastine (CLM) targets NLRP3 in hypoxic brain …

Abnormalities in myelination are associated to behavioral and cognitive dysfunction in
neurodevelopmental psychiatric disorders. Thus, therapies to promote or accelerate …

Westernization of dietary habits has led to a progressive reduction in dietary intake of n‐3
polyunsaturated fatty acids (n‐3 PUFAs). Low maternal intake of n‐3 PUFAs has been linked …

Background Preterm white matter injury (PWMI) is the most common cause of brain injury in
premature neonates. PWMI involves a differentiation arrest of oligodendrocytes, the …

The concept of the gut-brain axis has focused research on how gut dysbiosis affects myelin
biology in the brain. However, this axis has not been tested to determine whether it conveys …

Patients with chronic pain often experience memory impairment, but the underlying
mechanisms remain elusive. The myelin sheath is crucial for rapid and accurate action …

Objectives Optic neuritis (ON) is the most common cause of optic neuropathy; typically
presenting with a unilateral visual loss in young adults, with incidence of 1–5 in 100,000 per …