Curcumin‐piperine co‐supplementation and human health: a comprehensive review of preclinical and clinical studies

H Heidari, M Bagherniya, M Majeed… - Phytotherapy …, 2023 - Wiley Online Library
Curcumin is extracted from the rhizomes Curcuma longa L. It is known for its anti‐
inflammatory and anti‐oxidant activities. Despite its safety and potential for use against …

Curcumin, inflammation, and chronic diseases: how are they linked?

Y He, Y Yue, X Zheng, K Zhang, S Chen, Z Du - Molecules, 2015 - mdpi.com
It is extensively verified that continued oxidative stress and oxidative damage may lead to
chronic inflammation, which in turn can mediate most chronic diseases including cancer …

Co-delivery of curcumin and piperine in zein-carrageenan core-shell nanoparticles: Formation, structure, stability and in vitro gastrointestinal digestion

S Chen, Q Li, DJ McClements, Y Han, L Dai, L Mao… - Food …, 2020 - Elsevier
Core-shell biopolymer nanoparticles were fabricated using a hydrophobic protein (zein) as
the core and a hydrophilic anionic polysaccharide (ι-carrageenan) as the shell. The outer …

Protective effect of curcumin against heavy metals-induced liver damage

WR García-Niño, J Pedraza-Chaverrí - Food and chemical toxicology, 2014 - Elsevier
Occupational or environmental exposures to heavy metals produce several adverse health
effects. The common mechanism determining their toxicity and carcinogenicity is the …

Core–shell biopolymer nanoparticles for co-delivery of curcumin and piperine: Sequential electrostatic deposition of hyaluronic acid and chitosan shells on the zein …

S Chen, DJ McClements, L Jian, Y Han… - … applied materials & …, 2019 - ACS Publications
Curcumin and piperine are natural nutraceuticals that exhibit synergistic biological activities,
but have different polarities, which can make their encapsulation within a single delivery …

Potential protective roles of curcumin against cadmium-induced toxicity and oxidative stress

JH Park, BM Lee, HS Kim - Journal of Toxicology and …, 2021 - Taylor & Francis
Curcumin, used as a spice and traditional medicine in India, exerts beneficial effects against
several diseases, owing to its antioxidant, analgesic, and anti-inflammatory properties …

[HTML][HTML] Therapeutic potential and limitations of curcumin as antimetastatic agent

P Dytrych, Z Kejík, J Hajduch, R Kaplánek… - Biomedicine & …, 2023 - Elsevier
Abstract Treatment of metastatic cancer is one of the biggest challenges in anticancer
therapy. Curcumin is interesting nature polyphenolic compound with unique biological and …

Piperine and its role in chronic diseases

G Derosa, P Maffioli, A Sahebkar - Anti-inflammatory nutraceuticals and …, 2016 - Springer
Alkaloids include a family of naturally occurring chemical compounds containing mostly
basic nitrogen atoms. Piperine is an alkaloid present in black pepper (Piper nigrum), one of …

Role of herbal bioactives as a potential bioavailability enhancer for active pharmaceutical ingredients

A Alexander, A Qureshi, L Kumari, P Vaishnav… - Fitoterapia, 2014 - Elsevier
The current review emphasizes on the herbal bioenhancers which themselves do not
possess inherent pharmacological activity of their own but when co-administered with Active …

Polyphenols: Major regulators of key components of DNA damage response in cancer

M Majidinia, A Bishayee, B Yousefi - DNA repair, 2019 - Elsevier
DNA fidelity is constantly endangered by various types of intrinsic damages and extrinsic
damages. Cells that are affected by DNA damage employ a specific, intricate, and …