Harnessing abiotic organic chemistry in living systems for biomedical applications

J Wu, J Lin, P Huang - Chemical Society Reviews, 2023 - pubs.rsc.org
Living systems are composed of a complex network of bioactive small molecules, proteins,
ions and electrons, which present a wealth of opportunities for researchers to explore …

[HTML][HTML] Harnessing reactive oxygen/nitrogen species and inflammation: Nanodrugs for liver injury

M Liu, Q Huang, Y Zhu, L Chen, Y Li, Z Gong, K Ai - Materials Today Bio, 2022 - Elsevier
Overall, 12% of the global population (800 million) suffers from liver disease, which causes 2
million deaths every year. Liver injury involving characteristic reactive oxygen/nitrogen …

Ultra‐Small High‐Entropy Alloy Nanoparticles: Efficient Nanozyme for Enhancing Tumor Photothermal Therapy

Y Ai, MQ He, H Sun, X Jia, L Wu, X Zhang… - Advanced …, 2023 - Wiley Online Library
High‐entropy alloys nanoparticles (HEANPs) are receiving extensive attention due to their
broad compositional tunability and unlimited potential in bioapplication. However …

Sensitive activatable nanoprobes for real‐time ratiometric magnetic resonance imaging of reactive oxygen species and ameliorating inflammation in vivo

X Li, Y Liu, X Qi, S Xiao, Z Xu, Z Yuan, Q Liu… - Advanced …, 2022 - Wiley Online Library
Imaging‐guided real‐time monitoring of the treatment process of inflammatory diseases is
important for the timely adjustment of treatment planning to lower unnecessary side effects …

In situ enzyme‐induced self‐assembly of antimicrobial‐antioxidative peptides to promote wound healing

R Teng, Y Yang, Z Zhang, K Yang… - Advanced Functional …, 2023 - Wiley Online Library
Antimicrobial peptides (AMPs) with dual intrinsic antibacterial and antioxidative functions
have emerged as promising choice to cure infected wound. However, the most widely …

Manipulating the antioxidative capacity of melanin-like nanoparticles by involving condensation polymerization

P Yang, T Wang, J Zhang, H Zhang, W Bai… - Science China …, 2023 - Springer
Melanin is ubiquitous in nature and plays important roles in physiological activities
especially in keeping the oxidative balance. Both natural and synthetic melanin were …

Stimulation-responsive mucoadhesive probiotics for inflammatory bowel disease treatment by scavenging reactive oxygen species and regulating gut microbiota

QX Huang, JL Liang, CH Yang, K Li, MT Niu, JX Fan… - Biomaterials, 2023 - Elsevier
Inflammatory bowel disease (IBD) is characterized by the high level of reactive oxygen
species (ROS) and highly dysfunctional intestinal flora. Here, a stimulation-responsive …

Inhaled pro‐efferocytic nanozymes promote resolution of acute lung injury

H Ji, C Zhang, F Xu, Q Mao, R Xia, M Chen… - Advanced …, 2022 - Wiley Online Library
Acute lung injury (ALI) is a significant contributor to the morbidity and mortality of sepsis.
Characterized by uncontrolled inflammation and excessive inflammatory cells infiltration in …

Recent applications of melanin-like nanoparticles as antioxidant agents

A Mavridi-Printezi, A Menichetti, D Mordini, R Amorati… - Antioxidants, 2023 - mdpi.com
Nanosized antioxidants are highly advantageous in terms of versatility and
pharmacokinetics, with respect to conventional molecular ones. Melanin-like materials …

Biodegradable MoSe2-polyvinylpyrrolidone nanoparticles with multi-enzyme activity for ameliorating acute pancreatitis

P Xie, L Zhang, H Shen, H Wu, J Zhao, S Wang… - Journal of …, 2022 - Springer
Exogenous antioxidant materials mimicking endogenous antioxidant systems are commonly
used for the treatment of oxidative stress-induced injuries. Thus, artificial enzymes have …