Parvalbumin-positive interneurons regulate cortical sensory plasticity in adulthood and development through shared mechanisms

DD Rupert, SD Shea - Frontiers in Neural Circuits, 2022 - frontiersin.org
Parvalbumin-positive neurons are the largest class of GABAergic, inhibitory neurons in the
central nervous system. In the cortex, these fast-spiking cells provide feedforward and …

Acute fasting modulates food-seeking behavior and neural signaling in the piriform cortex

FY Ngo, H Li, H Zhang, CYG Lau - Nutrients, 2022 - mdpi.com
It is well known that the state of hunger can modulate hormones and hypothalamic neural
circuits to drive food-seeking behavior and consumption. However, the role the sensory …

TNF-α orchestrates experience-dependent plasticity of excitatory and inhibitory synapses in the anterior piriform cortex

A Guo, CG Lau - Frontiers in Neuroscience, 2022 - frontiersin.org
Homeostatic synaptic plasticity, which induces compensatory modulation of synapses, plays
a critical role in maintaining neuronal circuit function in response to changing activity …

Suppression of piriform cortex alters brain-wide dynamics and alleviates seizures in temporal lobe epilepsy

H Zhang, A Chiu, H Jiang, HMC Choi, Z Huang… - bioRxiv, 2023 - biorxiv.org
Temporal lobe epilepsy (TLE) is a pathological state that involves altered excitation-
inhibition (EI) in the brain and exhibits recurrent seizures. Many circuit studies of TLE have …

Non-cell autonomous OTX2 in the piriform cortex regulates parvalbumin cell maturation states and olfactory-driven behavior

R Gibel-Russo, AA Di Nardo - bioRxiv, 2024 - biorxiv.org
The timing of critical periods of juvenile brain plasticity is driven by the maturation of
parvalbumin interneurons in the neocortex, a process regulated in part by non-cell …

Auditory Cortex Inhibitory Interneurons and Their Plasticity in the Context of Methyl CpG Binding Protein 2 Mutation

DD Rupert - 2022 - search.proquest.com
Rett Syndrome (RTT) is a pervasive, neurodevelopmental disorder previously classified as a
syndromic type of Autism Spectrum Disorders (ASDs). Unlike ASDs, RTT is monogenic …

Étude de la signalisation de l'homéoprotéine OTX2 dans les cortex piriforme et visuel adultes pour la maturation des interneurones et la plasticité fonctionnelle

R Gibel-Russo - 2022 - theses.hal.science
Le cortex piriforme est une structure singulière recevant des afférences directes du bulbe
olfactif. Son renouvellement neuronal partiel pourrait conférer un état de plasticité important …