Mycobacterial infections in adults with haematological malignancies and haematopoietic stem cell transplants: guidelines from the 8th European Conference on …

A Bergeron, M Mikulska, J De Greef… - The Lancet Infectious …, 2022 - thelancet.com
Mycobacterial infections, both tuberculosis and nontuberculous, are more common in
patients with haematological malignancies and haematopoietic stem cell transplant …

Advances in diagnostics and drug discovery against resistant and latent tuberculosis infection

C Shleider Carnero Canales, J Marquez Cazorla… - Pharmaceutics, 2023 - mdpi.com
Latent tuberculosis infection (LTBI) represents a subclinical, asymptomatic mycobacterial
state affecting approximately 25% of the global population. The substantial prevalence of …

Occurrence and human health risk assessment of antibiotics in cultured fish from 19 provinces in China

Y Tang, X Lou, G Yang, L Tian, Y Wang… - Frontiers in Cellular and …, 2022 - frontiersin.org
The occurrence of antibiotics and potential health risk of 300 cultured fish samples from 19
provinces in China were investigated. The levels of 28 antibiotics (15 fluoroquinolones, 4 …

Translational assessment of drug‐induced proximal tubule injury using a kidney microphysiological system

C Maass, NB Sorensen, J Himmelfarb… - CPT …, 2019 - Wiley Online Library
Drug‐induced kidney injury, a major cause of acute kidney injury, results in progressive
kidney disease and is linked to increased mortality in hospitalized patients. Primary injury …

Targeting isocitrate lyase for the treatment of latent tuberculosis

RP Bhusal, G Bashiri, BXC Kwai, J Sperry… - Drug Discovery …, 2017 - Elsevier
Highlights•Isocitrate lyase (ICL) is essential to growth and survival of Mycobacterium
tuberculosis (Mtb).•ICL is involved in Mtb glyoxylate and methylisocitrate cycles, and may …

The COVID-19/tuberculosis syndemic and potential antibody therapy for TB based on the lessons learnt from the pandemic

SA Dass, V Balakrishnan, N Arifin, CSY Lim… - Frontiers in …, 2022 - frontiersin.org
2020 will be marked in history for the dreadful implications of the COVID-19 pandemic that
shook the world globally. The pandemic has reshaped the normality of life and affected …

Studies on the interaction of antibiotic drug rifampin with DNA and influence of bivalent metal ions on binding affinity

N Shahabadi, F Shiri, S Hadidi - Spectrochimica Acta Part A: Molecular and …, 2019 - Elsevier
In this paper, the interaction between rifampin, a known antibiotic used against tuberculosis,
and DNA helix is investigated by applying multiple biophysical and molecular modelling …

Fluoroquinolone therapy for the prevention of multidrug-resistant tuberculosis in contacts. A cost-effectiveness analysis

GJ Fox, O Oxlade, D Menzies - American journal of respiratory and …, 2015 - atsjournals.org
Rationale: Fluoroquinolone (FQN) therapy of latent tuberculosis infection among contacts of
individuals with multidrug-resistant tuberculosis (MDR-TB) is controversial. Objectives: To …

Assessing therapeutic potential of molecules: molecular property diagnostic suite for tuberculosis

AS Gaur, A Bhardwaj, A Sharma, L John… - Journal of Chemical …, 2017 - Springer
Abstract Molecular Property Diagnostic Suite (MPDS^ TB MPDS TB) is a web tool
(http://mpds. osdd. net) designed to assist the in silico drug discovery attempts towards …

Diagnosis and management of latent tuberculosis

ML Turetz, KC Ma - Current Opinion in Infectious Diseases, 2016 - journals.lww.com
Identification of those with LTBI is important as it allows treatment of those at highest risk of
progression to active disease and thus decreases the overall burden of tuberculosis. The …