Mast cells and their progenitors in allergic asthma

E Méndez-Enríquez, J Hallgren - Frontiers in immunology, 2019 - frontiersin.org
Mast cells and their mediators have been implicated in the pathogenesis of asthma and
allergy for decades. Allergic asthma is a complex chronic lung disease in which several …

Synthesis, functionalization, and design of magnetic nanoparticles for theranostic applications

J Mosayebi, M Kiyasatfar… - Advanced Healthcare …, 2017 - Wiley Online Library
In order to translate nanotechnology into medical practice, magnetic nanoparticles (MNPs)
have been presented as a class of non‐invasive nanomaterials for numerous biomedical …

Different activation signals induce distinct mast cell degranulation strategies

N Gaudenzio, R Sibilano, T Marichal… - The Journal of …, 2016 - Am Soc Clin Investig
Mast cells (MCs) influence intercellular communication during inflammation by secreting
cytoplasmic granules that contain diverse mediators. Here, we have demonstrated that MCs …

Magnetic iron oxide nanoparticles for multimodal imaging and therapy of cancer

R Thomas, IK Park, YY Jeong - International journal of molecular sciences, 2013 - mdpi.com
Superparamagnetic iron oxide nanoparticles (SPION) have emerged as an MRI contrast
agent for tumor imaging due to their efficacy and safety. Their utility has been proven in …

Emerging concepts: mast cell involvement in allergic diseases

BD Modena, K Dazy, AA White - Translational Research, 2016 - Elsevier
In a process known as overt degranulation, mast cells can release all at once a diverse array
of products that are preformed and present within cytoplasmic granules. This occurs typically …

Synthesis and characterization of superparamagnetic iron-oxide nanoparticles (SPIONs) and utilization of SPIONs in X-ray imaging

C Justin, SA Philip, AV Samrot - Applied Nanoscience, 2017 - Springer
The versatility of superparamagnetic iron-oxide nanoparticles (SPIONs) have been
extensively investigated, especially for their applications in therapeutics and diagnostics …

An update on nanoparticle-based contrast agents in medical imaging

N Naseri, E Ajorlou, F Asghari… - Artificial Cells …, 2018 - Taylor & Francis
Despite the great value of current exogenous contrast agents for providing main diagnostic
information, they still have certain drawbacks such as short blood half life, nonspecific …

Kappa opioids inhibit spinal output neurons to suppress itch

TD Sheahan, CA Warwick, AY Cui, DAA Baranger… - Science …, 2024 - science.org
Itch is a protective sensation that drives scratching. Although specific cell types have been
proposed to underlie itch, the neural basis for itch remains unclear. Here, we used two …

Drug-induced pseudoallergy: a review of the causes and mechanisms

B Zhang, Q Li, C Shi, X Zhang - Pharmacology, 2017 - karger.com
Adverse drug reactions occur frequently and can trigger pseudoallergy, which has become a
serious threat to public health. Pseudoallergy is a typical non-immune anaphylactic reaction …

Preclinical validation of the utility of BLZ-100 in providing fluorescence contrast for imaging spontaneous solid tumors

J Fidel, KC Kennedy, WS Dernell, S Hansen, V Wiss… - Cancer research, 2015 - AACR
There is a need in surgical oncology for contrast agents that can enable real-time
intraoperative visualization of solid tumors that can enable complete resections while …