Mantle-cell lymphoma

JO Armitage, DL Longo - New England Journal of Medicine, 2022 - Mass Medical Soc
Mantle-Cell Lymphoma Accounting for 5 to 7% of all lymphomas, mantle-cell lymphoma has
historically been associated with a poor outcome, but survival is improving. The …

Mantle cell lymphoma: 2019 update on the diagnosis, pathogenesis, prognostication, and management

P Jain, M Wang - American journal of hematology, 2019 - Wiley Online Library
Unprecedented advances in our understanding of the pathobiology, prognostication, and
therapeutic options in mantle cell lymphoma (MCL) have taken place in the last few years …

Mantle cell lymphoma in 2022—A comprehensive update on molecular pathogenesis, risk stratification, clinical approach, and current and novel treatments

P Jain, ML Wang - American journal of hematology, 2022 - Wiley Online Library
The field of mantle cell lymphoma (MCL) has witnessed remarkable progress due to
relentless advances in molecular pathogenesis, prognostication, and newer treatments …

Chemokines in triple-negative breast cancer heterogeneity: new challenges for clinical implications

U Mehraj, U Mushtaq, MA Mir, A Saleem… - Seminars in Cancer …, 2022 - Elsevier
Tumor heterogeneity is a hallmark of cancer and one of the primary causes of resistance to
therapies. Triple-negative breast cancer (TNBC), which accounts for 15–20% of all breast …

Treatment outcomes and roles of transplantation and maintenance rituximab in patients with previously untreated mantle cell lymphoma: results from large real-world …

P Martin, JB Cohen, M Wang, A Kumar, B Hill… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Commonly used first-line (1L) treatments for mantle cell lymphoma include high-
dose cytarabine-based induction followed by autologous stem-cell transplant (ASCT) for …

Outcomes in first relapsed-refractory younger patients with mantle cell lymphoma: results from the MANTLE-FIRST study

C Visco, A Di Rocco, A Evangelista, FM Quaglia… - Leukemia, 2021 - nature.com
Patients with mantle cell lymphoma (MCL) that fail induction treatment represent a difficult-to-
treat population, where no standard therapy exists. We evaluated outcomes in patients with …

Brexucabtagene autoleucel for the treatment of relapsed/refractory mantle cell lymphoma

A Mian, BT Hill - Expert opinion on biological therapy, 2021 - Taylor & Francis
Introduction: The therapeutic options for mantle cell lymphoma (MCL) include traditional
chemo-immunotherapy for newly diagnosed cases, and targeted treatments including the …

Long-term survival of patients with mantle cell lymphoma after autologous haematopoietic stem-cell transplantation in first remission: a post-hoc analysis of an open …

AK Zoellner, M Unterhalt, S Stilgenbauer… - The Lancet …, 2021 - thelancet.com
Background Autologous haematopoietic stem-cell transplantation (HSCT) in first remission
is the current standard treatment in fit patients with mantle cell lymphoma. In this long-term …

Emerging therapies in mantle cell lymphoma

W Hanel, N Epperla - Journal of hematology & oncology, 2020 - Springer
Mantle cell lymphoma (MCL) is a rare, B cell non-Hodgkin's lymphoma with highly
heterogeneous clinical presentation and aggressiveness. First-line treatment consists of …

Lenalidomide maintenance after autologous haematopoietic stem-cell transplantation in mantle cell lymphoma: results of a Fondazione Italiana Linfomi (FIL) …

M Ladetto, S Cortelazzo, S Ferrero… - The Lancet …, 2021 - thelancet.com
Background Fit patients with mantle cell lymphoma aged 18–65 years are usually given
cytarabine and rituximab-based induction regimens followed by autologous haematopoetic …