Regrow or repair: potential regenerative therapies for the kidney

MH Little - Journal of the American Society of Nephrology, 2006 - journals.lww.com
Regenerative medicine is being heralded in a similar way as gene therapy was some 15 yr
ago. It is an area of intense excitement and potential, as well as myth and disinformation …

Somatic cell nuclear transfer in pigs: recent achievements and future possibilities

G Vajta, Y Zhang, Z Macháty - Reproduction, Fertility and …, 2007 - CSIRO Publishing
During the past 6 years, considerable advancement has been achieved in experimental
embryology of pigs. This process was mainly generated by the rapidly increasing need for …

[图书][B] Swine in the laboratory: surgery, anesthesia, imaging, and experimental techniques

MM Swindle - 2007 - taylorfrancis.com
To diminish the learning curve associated with using swine as models, Swine in the
Laboratory: Surgery, Anesthesia, Imaging, and Experimental Techniques, Second Edition …

Functional skeletal muscle regeneration from differentiating embryonic stem cells

R Darabi, K Gehlbach, RM Bachoo, S Kamath… - Nature medicine, 2008 - nature.com
Little progress has been made toward the use of embryonic stem (ES) cells to study and
isolate skeletal muscle progenitors. This is due to the paucity of paraxial mesoderm …

Preconditioning allows engraftment of mouse and human embryonic lung cells, enabling lung repair in mice

C Rosen, E Shezen, A Aronovich, YZ Klionsky… - Nature medicine, 2015 - nature.com
Repair of injured lungs represents a longstanding therapeutic challenge. We show that
human and mouse embryonic lung tissue from the canalicular stage of development (20–22 …

Identification of human nephron progenitors capable of generation of kidney structures and functional repair of chronic renal disease

O Harari‐Steinberg, S Metsuyanim, D Omer… - EMBO molecular …, 2013 - embopress.org
Identification of tissue‐specific renal stem/progenitor cells with nephrogenic potential is a
critical step in developing cell‐based therapies for renal disease. In the human kidney …

[HTML][HTML] Skeletal muscle stem cells from PSC-derived teratomas have functional regenerative capacity

SSK Chan, RW Arpke, A Filareto, N Xie, MP Pappas… - Cell Stem Cell, 2018 - cell.com
Derivation of functional skeletal muscle stem cells from pluripotent cells without genetic
modification has proven elusive. Here we show that teratomas formed in adult skeletal …

Stem-cell approaches for kidney repair: choosing the right cells

C Sagrinati, E Ronconi, E Lazzeri, L Lasagni… - Trends in molecular …, 2008 - cell.com
With the increasing rate of end-stage renal failure and limited alternatives for its treatment,
stem cell (SC) therapy for kidney injury is urgently needed. Choosing the right SC type is the …

Embryonic pig pancreatic tissue for the treatment of diabetes in a nonhuman primate model

G Hecht, S Eventov-Friedman… - Proceedings of the …, 2009 - National Acad Sciences
Xenotransplantation of pig tissues has great potential to overcome the shortage of organ
donors. One approach to address the vigorous immune rejection associated with …

Transplantation of 3D scaffolds seeded with human embryonic stem cells: biological features of surrogate tissue and teratoma-forming potential

JG Lees, SA Lim, T Croll, G Williams, S Lui… - Regenerative …, 2007 - Taylor & Francis
Aim: To generate complex surrogate tissue by transplanting 3D scaffolds seeded with
human embryonic stem cells (hESCs) between the liver lobules of severe combined …