Scientific research and progress, particularly in the drug discovery and regenerative
medicine fields, is typically dependent on suitable animal models to develop new and …

Engineering bone tissue for use in orthopaedics poses multiple challenges. Providing the
appropriate growth environment that will allow complex tissues such as bone to grow is one …

This eight-chapter monograph intends to present basic principles and applications of
biomechanics in bone tissue engineering in order to assist tissue engineers in design and …

Bone metastasis represents the leading cause of breast cancer related-deaths. However,
the effect of skeleton-associated biomechanical signals on the initiation, progression, and …

This works reports the development and preliminary assessment of a new bioreactor for
culturing large‐sized three‐dimensional constructs in bone tissue engineering. The …

This work evaluated in vivo performance of a tissue-engineered bone-like matrix obtained
by culturing cell-scaffold constructs in a flow perfusion bioreactor, designed to enable culture …

The first work hypotesis is that biosensors on the patient detecting heart, breath rate and skin
parameters, modulate laser radiation to enhance the therapeutic outcome; in the second …

The Authors describe a new biosensor‐related approach to LLT delivery, tailored to
homogeneously integrate the external energy to the maximum patient compliance and …

After several decades of endeavor, tissue engineers and researchers have realized that
synergetic efforts from multiple disciplines in engineering, biology, physics, chemistry, and …

Reaction-diffusion mechanisms underlie communication of cells within and among
themselves and also with their environment. In this thesis, I have developed computational …