Animals transmit not only DNA but also other molecules, such as RNA, proteins and
metabolites, to their progeny via gametes. It is currently unclear to what extent these …

The idea that epigenetic determinants such as DNA methylation, histone modifications or
RNA can be passed to the next generation through meiotic products (gametes) is long …

BACKGROUND It has long been thought that the factors affecting embryo and foetal
development were exclusively maternally derived; hence, if issues regarding fertility and …

Since the human genome was sequenced, the term" epigenetics" is increasingly being
associated with the hope that we are more than just the sum of our genes. Might what we …

Our highly seasonal world restricts insect activity to brief portions of the year. This feature
necessitates a sophisticated interpretation of seasonal changes and enactment of …

Ageing is affected by both genetic and non-genetic factors. Here, we review the chromatin-
based epigenetic changes that occur during ageing, the role of chromatin modifiers in …

In mammalian cells, DNA methylation on the fifth position of cytosine (5mC) plays an
important role as an epigenetic mark. However, DNA methylation was considered to be …

INTRODUCTION Despite the father transmitting half of the heritable information to the
embryo, the focus of preconception health has been the mother. Paternal effects have been …

Research efforts during the past decades have provided intriguing evidence suggesting that
stressful experiences during pregnancy exert long-term consequences on the future mental …

Organisms require an appropriate balance of stability and reversibility in gene expression
programmes to maintain cell identity or to enable responses to stimuli; epigenetic regulation …