The essential elements of Alzheimer's disease

P Lei, S Ayton, AI Bush - Journal of Biological Chemistry, 2021 - ASBMB
Treatments for Alzheimer's disease (AD) directed against the prominent amyloid plaque
neuropathology are yet to be proved effective despite many phase 3 clinical trials. There are …

Chronic stress and oxidative stress as common factors of the pathogenesis of depression and Alzheimer's disease: The role of antioxidants in prevention and …

G Juszczyk, J Mikulska, K Kasperek, D Pietrzak… - Antioxidants, 2021 - mdpi.com
There is a growing body of scientific research showing the link between depression and
dementia in Alzheimer's disease (AD). The chronic stress contributes to the formation of …

Metals and neurodegenerative diseases. A systematic review

CE Cicero, G Mostile, R Vasta, V Rapisarda… - Environmental …, 2017 - Elsevier
Neurodegenerative processes encompass a large variety of diseases with different
pathological patterns and clinical presentation such as Amyotrophic Lateral Sclerosis (ALS) …

Oxidative stress and cognitive decline: the neuroprotective role of natural antioxidants

F Franzoni, G Scarfò, S Guidotti, J Fusi… - Frontiers in …, 2021 - frontiersin.org
Free-radicals (Oxygen and Nitrogen species) are formed in mitochondria during the
oxidative phosphorylation. Their high reactivity, due to not-engaged electrons, leads to an …

Brazil nuts: Nutritional composition, health benefits and safety aspects

BR Cardoso, GBS Duarte, BZ Reis… - Food Research …, 2017 - Elsevier
Brazil nuts are among the richest selenium food sources, and studies have considered this
Amazonian nut as an alternative for selenium supplementation. Besides selenium, Brazil …

Role of environmental contaminants in the etiology of Alzheimer's disease: a review

M Yegambaram, B Manivannan… - Current Alzheimer …, 2015 - ingentaconnect.com
Alzheimer's dis ease (AD) is a leading cause of mortality in the developed world with 70%
risk attributable to genetics. The remaining 30% of AD risk is hypothesized to include …

[HTML][HTML] Plasma nutrient status of patients with Alzheimer's disease: systematic review and meta-analysis

SL da Silva, B Vellas, S Elemans, J Luchsinger… - Alzheimer's & …, 2014 - Elsevier
Background Alzheimer disease (AD) patients are at risk of nutritional insufficiencies because
of physiological and psychological factors. Nutritional compounds are postulated to play a …

Selenium, selenoproteins and neurodegenerative diseases

BR Cardoso, BR Roberts, AI Bush, DJ Hare - Metallomics, 2015 - academic.oup.com
It is unsurprising that our understanding of the role of selenium in neurological function is
somewhat immature, considering its relatively recent discovery as an essential element to …

Effects of selenium supplementation in patients with mild cognitive impairment or Alzheimer's disease: A systematic review and meta-analysis

ME Pereira, JV Souza, MEA Galiciolli, F Sare… - Nutrients, 2022 - mdpi.com
Elevated levels of oxidative stress could cause and aggravate Alzheimer's disease (AD).
Selenium (Se) is a trace element with antioxidant and anti-inflammatory activity with …

Roles of selenoproteins in brain function and the potential mechanism of selenium in Alzheimer's disease

ZH Zhang, GL Song - Frontiers in Neuroscience, 2021 - frontiersin.org
Selenium (Se) and its compounds have been reported to have great potential in the
prevention and treatment of Alzheimer's disease (AD). However, little is known about the …