[HTML][HTML] The glymphatic system: Current understanding and modeling
We review theoretical and numerical models of the glymphatic system, which circulates
cerebrospinal fluid and interstitial fluid around the brain, facilitating solute transport. Models …
cerebrospinal fluid and interstitial fluid around the brain, facilitating solute transport. Models …
Ischaemic stroke
Stroke is the second highest cause of death globally and a leading cause of disability, with
an increasing incidence in developing countries. Ischaemic stroke caused by arterial …
an increasing incidence in developing countries. Ischaemic stroke caused by arterial …
[HTML][HTML] Ischemia-triggered glutamate excitotoxicity from the perspective of glial cells
D Belov Kirdajova, J Kriska, J Tureckova… - Frontiers in cellular …, 2020 - frontiersin.org
A plethora of neurological disorders shares a final common deadly pathway known as
excitotoxicity. Among these disorders, ischemic injury is a prominent cause of death and …
excitotoxicity. Among these disorders, ischemic injury is a prominent cause of death and …
The pathophysiology of migraine: implications for clinical management
A Charles - The Lancet Neurology, 2018 - thelancet.com
The understanding of migraine pathophysiology is advancing rapidly. Improved
characterisation and diagnosis of its clinical features have led to the view of migraine as a …
characterisation and diagnosis of its clinical features have led to the view of migraine as a …
[HTML][HTML] Real-time whole-brain imaging of hemodynamics and oxygenation at micro-vessel resolution with ultrafast wide-field photoacoustic microscopy
High-speed high-resolution imaging of the whole-brain hemodynamics is critically important
to facilitating neurovascular research. High imaging speed and image quality are crucial to …
to facilitating neurovascular research. High imaging speed and image quality are crucial to …
Cerebrospinal fluid influx drives acute ischemic tissue swelling
INTRODUCTION Cerebrospinal fluid (CSF) covers and protects the brain from mechanical
injury. CSF also flows along an interconnected network of perivascular spaces surrounding …
injury. CSF also flows along an interconnected network of perivascular spaces surrounding …
[HTML][HTML] Neutrophils obstructing brain capillaries are a major cause of no-reflow in ischemic stroke
Despite successful clot retrieval in large vessel occlusion stroke,∼ 50% of patients have an
unfavorable clinical outcome. The mechanisms underlying this functional reperfusion failure …
unfavorable clinical outcome. The mechanisms underlying this functional reperfusion failure …
Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial …
P Toth, S Tarantini, A Csiszar… - American Journal of …, 2017 - journals.physiology.org
Increasing evidence from epidemiological, clinical and experimental studies indicate that
age-related cerebromicrovascular dysfunction and microcirculatory damage play critical …
age-related cerebromicrovascular dysfunction and microcirculatory damage play critical …
[HTML][HTML] The physiology of regulated BDNF release
T Brigadski, V Leßmann - Cell and Tissue Research, 2020 - Springer
The neurotrophic factor BDNF is an important regulator for the development of brain circuits,
for synaptic and neuronal network plasticity, as well as for neuroregeneration and …
for synaptic and neuronal network plasticity, as well as for neuroregeneration and …
Impaired neurovascular coupling in aging and Alzheimer's disease: contribution of astrocyte dysfunction and endothelial impairment to cognitive decline
The importance of (micro) vascular contributions to cognitive impairment and dementia
(VCID) in aging cannot be overemphasized, and the pathogenesis and prevention of age …
(VCID) in aging cannot be overemphasized, and the pathogenesis and prevention of age …