Reactive oxygen species (ROS) are generated as by-products of normal cellular metabolic
activities. Superoxide dismutase, glutathione peroxidase, and catalase are the enzymes …

Arsenic contamination of groundwater in different parts of the world is an outcome of natural
and/or anthropogenic sources, leading to adverse effects on human health and ecosystem …

Reactive oxygen species (ROS) are generated during mitochondrial oxidative metabolism
as well as in cellular response to xenobiotics, cytokines, and bacterial invasion. Oxidative …

Inflammatory conditions in selected organs increase the risk of cancer. An inflammatory
component is present also in the microenvironment of tumors that are not epidemiologically …

Abstract Arsenic (As) and selenium (Se) are unusual metalloids as they both induce and
cure cancer. They both cause carcinogenesis, pathology, cytotoxicity, and genotoxicity in …

S-adenosylmethionine (AdoMet, also known as SAM and SAMe) is the principal biological
methyl donor synthesized in all mammalian cells but most abundantly in the liver …

Reactive oxygen species are produced by all aerobic cells and are widely believed to play a
pivotal role in aging as well as a number of degenerative diseases. The consequences of …

Genomic DNA is susceptible to endogenous and environmental stresses that modify DNA
structure and its coding potential. Correspondingly, cells have evolved intricate DNA repair …

Base excision repair (BER) is an evolutionarily conserved process for maintaining genomic
integrity by eliminating several dozen damaged (oxidized or alkylated) or inappropriate …

Bleomycins are a family of glycopeptide antibiotics that have potent antitumour activity
against a range of lymphomas, head and neck cancers and germ-cell tumours. The …