Titanium and titanium alloys exhibit a unique combination of strength and biocompatibility,
which enables their use in medical applications and accounts for their extensive use as …

This review describes the role of bone cells and their surrounding matrix in maintaining
bone strength through the process of bone remodeling. Subsequently, this work focusses on …

Surface topography impacts on cell growth and differentiation, but it is not trivial to generate
defined surface structures and to assess the relevance of specific topographic parameters …

Topography, among other physical factors such as substrate stiffness and extracellular
forces, is known to have a great influence on cell behaviours. Optimization of topographical …

In the body, cells inhabit within a complex three-dimensional (3D) extracellular matrix that
provides physical and chemical signals to regulate the cell fate. Cultured cells in Petri dishes …

The cellular environment impacts a myriad of cellular functions by providing signals that can
modulate cell phenotype and function. Physical cues such as topography, roughness …

The biological fixation between the dental implant surfaces and jaw bones should be
considered a prerequisite for the long-term success of implant-supported prostheses. In this …

In tissue engineering and regenerative medicine, the conditions in the immediate vicinity of
the cells have a direct effect on cells' behaviour and subsequently on clinical outcomes …

Membranes are fundamental elements within organ-on-a-chip (OOC) platforms, as they
provide adherent cells with support, allow nutrients (and other relevant molecules) to …

Repairing large bone defects caused by severe trauma or tumor resection remains one of
the major challenges in orthopedics and maxillofacial surgery. A promising therapeutic …