The great obstetrical syndromes and the placenta

MK Hoffman - BJOG: An International Journal of Obstetrics & …, 2023 - Wiley Online Library
Although historically pre‐eclampsia, preterm birth, abruption, fetal growth restriction and
stillbirth have been viewed as clinically distinct entities, a growing body of literature has …

Developmental programming in human umbilical cord vein endothelial cells following fetal growth restriction

F Terstappen, JJA Calis, ND Paauw, JA Joles… - Clinical …, 2020 - Springer
Background Fetal growth restriction (FGR) is associated with an increased susceptibility for
various noncommunicable diseases in adulthood, including cardiovascular and renal …

FPR2 serves a role in recurrent spontaneous abortion by regulating trophoblast function via the PI3K/AKT signaling pathway Corrigendum in/10.3892/mmr …

A Li, S Li, C Zhang, Z Fang, Y Sun… - Molecular …, 2021 - spandidos-publications.com
Recurrent spontaneous abortion (RSA) effects both the physical and mental health of
women of reproductive age. Trophoblast dysfunction may result in RSA due to shallow …

Suppression of FPR2 expression inhibits inflammation in preeclampsia by improving the biological functions of trophoblast via NF-κB pathway

S Li, A Li, L Zhai, Y Sun, L Yu, Z Fang, L Zhang… - Journal of assisted …, 2022 - Springer
Purpose The dysfunction of trophoblast during inflammation plays an important role in PE.
Formyl peptide receptor 2 (FPR2) plays crucial roles in the development of inflammation …

[PDF][PDF] COVID-19 during pregnancy alters circulating extracellular vesicle cargo and their effects on trophoblast.

TN Golden, S Mani, L Anton, CC Conine… - Biorxiv: the Preprint …, 2024 - scienceopen.com
SARS-CoV-2 infection and the resulting coronavirus disease (COVID-19) complicate
pregnancies as the result of placental dysfunction which increases the risk of adverse …

Extracellular vesicles alter trophoblast function in pregnancies complicated by COVID-19

TN Golden, S Mani, RL Linn, R Leite, NA Trigg… - bioRxiv, 2024 - biorxiv.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and resulting
coronavirus disease (COVID-19) causes placental dysfunction, which increases the risk of …

Combined Application of Exosomes and FPR2 Agonist LXA4 in Controlling Fetal Membrane Inflammation and Promoting Fetal Membrane Tissue Repair

X Huang, J Liao, F Feng, S Chen, E Liao, D Li… - Reproductive …, 2023 - Springer
Preterm premature rupture of membranes (pPROM) is a common pregnancy disease closely
related to inflammation. The formyl peptide receptor 2 (FPR2), a member of the G protein …

Liposome-Encapsulated Anti-inflammatory Proteins for Targeted Delivery to the Placenta to Treat Fetal Growth Restriction

P Murthi, LK Harris - Trophoblasts: Methods and Protocols, 2023 - Springer
Fetal growth restriction (FGR), the failure of a fetus to reach its genetically determined growth
potential, is a serious complication affecting up to 10% of pregnancies. FGR is a major risk …