The blood brain barrier (BBB) plays a critically important role in the regulation of central
nervous system (CNS) homeostasis, but also represents a major limitation to treatments of …

Blood-brain barrier (BBB) remains a significant obstacle to drug therapy for brain diseases.
Focused ultrasound (FUS) combined with microbubbles (MBs) can locally and transiently …

Glioblastoma (GBM) is the most devastating brain tumor and highly resistant to conventional
chemotherapy. Herein, we introduce biomimetic nanosonosensitizer systems (MDNPs) …

Brain tumors are particularly challenging malignancies, due to their location in a structurally
and functionally distinct part of the human body–the central nervous system (CNS). The CNS …

Ultrasound (US) is a mechanical wave that can penetrate biological tissues and trigger
complex bioeffects. The mechanisms of US in different diagnosis and treatment are different …

Simple Summary Glioblastoma (GBM) is a common primary brain tumor with a short median
overall survival despite aggressive treatment with resection, chemotherapy, and radiation …

An emerging approach with potential in improving the treatment of neurodegenerative
diseases and brain tumors is the use of focused ultrasound (FUS) to bypass the blood–brain …

Simple Summary Glioblastomas are the most common and aggressive brain tumors in
adults, with a median survival of 15 months. Treatment is surgical removal, followed by …

Though surgical biopsies provide direct access to tissue for genomic characterization of
brain cancer, they are invasive and pose significant clinical risks. Brain cancer management …

Survival outcomes for patients with glioblastoma multiforme (GBM) have remained poor for
the past 15 years, reflecting a clear challenge in the development of more effective treatment …