OBJECTIVE Unruptured intracranial aneurysms (UIAs) are relatively common lesions that
may cause devastating intracranial hemorrhage, thus producing considerable suffering and …

Chronic inflammation underlies various debilitating disorders including autoimmune,
neurodegenerative, vascular and metabolic diseases as well as cancer, where aberrant …

Ageing is characterized by the development of persistent pro-inflammatory responses that
contribute to atherosclerosis, metabolic syndrome, cancer and frailty,–. The ageing brain is …

Identifying drugs that regulate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) infection and its symptoms has been a pressing area of investigation during the …

SARS-CoV-2 causes acute respiratory distress that can progress to multiorgan failure and
death in a minority of patients. Although severe COVID-19 disease is linked to exuberant …

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is the cause of the novel
coronavirus disease 2019 (COVID‐19), a highly pathogenic and sometimes fatal respiratory …

Sex differences in cerebral aneurysm occurrence and characteristics have been well
described. Although sex differences in outcomes following ischemic stroke have been …

Intracranial aneurysm subarachnoid hemorrhage (SAH) is a cerebrovascular disorder
associated with high overall mortality. Currently, the underlying mechanisms of pathological …

Tumor-initiating stem cells (TSCs) are critical for drug resistance and immune escape.
However, the mutual regulations between TSC and tumor microenvironment (TME) remain …

Recent evidence has suggested that synovial inflammation and macrophage polarization
were involved in the pathogenesis of osteoarthritis (OA). Additionally, high-molecular-weight …