Glycosylation is a well-regulated cell and microenvironment specific post-translational
modification. Several glycosyltransferases and glycosidases orchestrate the addition of …

Carbohydrates are essential mediators of many processes in health and disease. They
regulate self-/non-self-discrimination, are key elements of cellular communication, cancer …

Sialic acids are cytoprotectors, mainly localized on the surface of cell membranes with
multiple and outstanding cell biological functions. The history of their structural analysis …

Every cell in nature carries a rich surface coat of glycans, its glycocalyx, which constitutes
the cell's interface with its environment. In eukaryotes, the glycocalyx is composed of …

O-acetylation is a common modification of sialic acids that has been implicated in a
multitude of biological and disease processes. A lack of analytical methods that can …

Liposomes are biodegradable and biocompatible lipid bilayer vesicles which are widely
exploited as preferred carriers for smart delivery of both hydrophobic as well as hydrophilic …

Glycans linked to proteins and lipids play key roles in biology; thus, accurate replication of
cellular glycans is crucial for maintaining function following cell division. The fact that …

Oligosaccharides together with oligonucleotides and oligopeptides comprise the three major
classes of natural biopolymers. Automated systems for oligonucleotide and oligopeptide …

Sialic acids (Sias) are abundant on vertebrate glycoproteins, glycolipids, and milk
oligosaccharides, as well as on some microbial surface glycans, mediating diverse …

Sialic acids are abundant on vertebrate glycoproteins and have diverse functional roles.
Originally discovered within the Deuterostome lineage of animals and associated microbes …