Neuroinflammatory pathways as treatment targets and biomarkers in epilepsy
A Vezzani, S Balosso, T Ravizza - Nature Reviews Neurology, 2019 - nature.com
Epilepsy is a chronic neurological disease characterized by an enduring propensity for
generation of seizures. The pathogenic processes of seizure generation and recurrence are …
generation of seizures. The pathogenic processes of seizure generation and recurrence are …
The role of inflammation in epilepsy
Epilepsy is the third most common chronic brain disorder, and is characterized by an
enduring predisposition to generate seizures. Despite progress in pharmacological and …
enduring predisposition to generate seizures. Despite progress in pharmacological and …
Cyclooxygenase-2 (COX-2) inhibitors: future therapeutic strategies for epilepsy management
Epilepsy, a common multifactorial neurological disease, affects about 69 million people
worldwide constituting nearly 1% of the world population. Despite decades of extensive …
worldwide constituting nearly 1% of the world population. Despite decades of extensive …
Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease
Neuronal expression of familial Alzheimer's disease–mutant human amyloid precursor
protein (hAPP) and hAPP-derived amyloid-β (Aβ) peptides causes synaptic dysfunction …
protein (hAPP) and hAPP-derived amyloid-β (Aβ) peptides causes synaptic dysfunction …
Role of inflammatory mediators in the pathogenesis of epilepsy
T Shimada, T Takemiya, H Sugiura… - Mediators of …, 2014 - Wiley Online Library
Epilepsy is one of the most common chronic brain disorders worldwide, affecting 1% of
people across different ages and backgrounds. Epilepsy is defined as the sporadic …
people across different ages and backgrounds. Epilepsy is defined as the sporadic …
Prostaglandin F2α receptor signaling facilitates bleomycin-induced pulmonary fibrosis independently of transforming growth factor-β
Idiopathic pulmonary fibrosis (IPF) is a progressive disease characterized by fibroblast
proliferation and excess deposition of collagen and other extracellular matrix (ECM) …
proliferation and excess deposition of collagen and other extracellular matrix (ECM) …
Therapeutic role of targeting mTOR signaling and neuroinflammation in epilepsy
Existing therapies for epilepsy are primarily symptomatic and target mechanisms of neuronal
transmission in order to restore the excitatory/inhibitory imbalance in the brain after seizures …
transmission in order to restore the excitatory/inhibitory imbalance in the brain after seizures …
Visualization of the cell-selective distribution of PUFA-containing phosphatidylcholines in mouse brain by imaging mass spectrometry [S]
Previous studies have shown that MALDI-imaging mass spectrometry (IMS) can be used to
visualize the distribution of various biomolecules, especially lipids, in the cells and tissues …
visualize the distribution of various biomolecules, especially lipids, in the cells and tissues …
Immune mechanisms in epileptogenesis
D Xu, SD Miller, S Koh - Frontiers in cellular neuroscience, 2013 - frontiersin.org
Epilepsy is a chronic brain disorder that affects 1% of the human population worldwide.
Immune responses are implicated in seizure induction and the development of epilepsy. Pre …
Immune responses are implicated in seizure induction and the development of epilepsy. Pre …
Chemokines as new inflammatory players in the pathogenesis of epilepsy
C Cerri, M Caleo, Y Bozzi - Epilepsy Research, 2017 - Elsevier
A large series of clinical and experimental studies supports a link between inflammation and
epilepsy, indicating that inflammatory processes within the brain are important contributors …
epilepsy, indicating that inflammatory processes within the brain are important contributors …