Hypertranscription: the invisible hand in stem cell biology

YK Kim, E Collignon, SB Martin, M Ramalho-Santos - Trends in Genetics, 2024 - cell.com
Stem cells are the fundamental drivers of growth during development and adult organ
homeostasis. The properties that define stem cells–self-renewal and differentiation–are …

Genetically Encoded Trensor Circuits Report HeLa Cell Treatment with Polyplexed Plasmid DNA and Small-Molecule Transfection Modulators

C Redwood-Sawyerr, G Howe… - ACS Synthetic …, 2024 - ACS Publications
HeLa cell transfection with plasmid DNA (pDNA) is widely used to materialize biologicals
and as a preclinical test of nucleic acid-based vaccine efficacy. We sought to genetically …

Finding order in chaos: Dissecting single-cell heterogeneity in space and time

C Gnann - 2024 - diva-portal.org
The cell is the smallest unit of life and contains DNA, RNA, proteins and a variety of other
macromolecules. In recent years, technological advances in the field of single cell biology …