Immune recognition occurs at specialized cell‐cell junctions when immune cells and target
cells physically touch. In this junction, groups of receptor‐ligand complexes assemble and …

Efficient scanning of tissue that T cells encounter during their migratory life is pivotal to
protective adaptive immunity. In fact, T cells can detect even a single antigenic peptide/MHC …

Focal adhesion kinase (FAK) relays integrin signaling from outside to inside cells and
contributes to cell adhesion and motility. However, the spatiotemporal dynamics of FAK …

Abstract Micro/nano-topography (MNT) is an important factor affecting cell response. Earlier
studies using titania (TiO 2) nanotube as a model of MNT found that they mediated the …

DNA‐PAINT enabled super‐resolution imaging through the transient binding of fluorescently‐
labelled single‐stranded DNA (ssDNA) imagers to target ssDNA. However, its performance …

Investigation of the biological system reveals many underlying principles that govern the
regular life processes. Recently, the analysis of tiny mechanical forces associated with many …

Molecular force sensors are a powerful tool for studying the mechanics of cells. These
sensors not only provide information on the general mechanical behavior of cells but also …

Focal adhesions (FAs) provide the cells linkages to extracellular matrix (ECM) at sites of
integrins binding and transmit mechanical forces between the ECM and the actin …

Single-molecule orientation-localization microscopy (SMOLM) builds upon super-resolved
localization microscopy by imaging orientations and rotational dynamics of individual …

Integrin receptors transduce the mechanical properties of the extracellular matrix. Past
studies using DNA probes showed that integrins sense the magnitude of ligand forces with …