Ischemia/reperfusion injury revisited: an overview of the latest pharmacological strategies

ROS Soares, DM Losada, MC Jordani, P Évora… - International journal of …, 2019 - mdpi.com
Ischemia/reperfusion injury (IRI) permeates a variety of diseases and is a ubiquitous
concern in every transplantation proceeding, from whole organs to modest grafts. Given its …

Global consequences of liver ischemia/reperfusion injury

C Nastos, K Kalimeris, N Papoutsidakis… - Oxidative medicine …, 2014 - Wiley Online Library
Liver ischemia/reperfusion injury has been extensively studied during the last decades and
has been implicated in the pathophysiology of many clinical entities following hepatic …

[HTML][HTML] Irisin alleviates liver ischemia-reperfusion injury by inhibiting excessive mitochondrial fission, promoting mitochondrial biogenesis and decreasing oxidative …

J Bi, J Zhang, Y Ren, Z Du, Q Li, Y Wang, S Wei… - Redox biology, 2019 - Elsevier
Current management of liver ischemia-reperfusion (I/R) injury is mainly based on supportive
care and no specific treatment is available. Irisin, a recently identified hormone, plays pivotal …

[HTML][HTML] Ischemia-reperfusion injury and its relationship with early allograft dysfunction in liver transplant patients

T Ito, BV Naini, D Markovic, A Aziz, S Younan… - American Journal of …, 2021 - Elsevier
Ischemia-reperfusion injury (IRI) is believed to contribute to graft dysfunction after liver
transplantation (LT). However, studies on IRI and the impact of early allograft dysfunction …

[HTML][HTML] Neutrophils: a cornerstone of liver ischemia and reperfusion injury

THC de Oliveira, PE Marques, P Proost… - Laboratory …, 2018 - Elsevier
Ischemia-reperfusion injury (IRI) is the main cause of morbidity and mortality due to graft
rejection after liver transplantation. During IRI, an intense inflammatory process occurs in the …

Brg1-mediated Nrf2/HO-1 pathway activation alleviates hepatic ischemia–reperfusion injury

M Ge, W Yao, D Yuan, S Zhou, X Chen, Y Zhang… - Cell Death & …, 2017 - nature.com
Cytoprotective gene heme oxygenase 1 (HO-1) could be induced by nuclear factor E2-
related factor 2 (Nrf2) nuclear translocation. The purpose of this study was to determine the …

The role of the NLRP3 inflammasome and programmed cell death in acute liver injury

C Yu, P Chen, L Miao, G Di - International Journal of Molecular Sciences, 2023 - mdpi.com
Acute liver injury (ALI) is a globally important public health issue that, when severe, rapidly
progresses to acute liver failure, seriously compromising the life safety of patients. The …

Autophagy and liver ischemia‐reperfusion injury

R Cursio, P Colosetti… - BioMed research …, 2015 - Wiley Online Library
Liver ischemia‐reperfusion (I‐R) injury occurs during liver resection, liver transplantation,
and hemorrhagic shock. The main mode of liver cell death after warm and/or cold liver I‐R is …

Molecular mechanisms and applications of tea polyphenols: A narrative review

Y Chen, S Cheng, J Dai, L Wang, Y Xu… - Journal of Food …, 2021 - Wiley Online Library
Tea is a worldwide popular drink with high nutritional and medicinal values as it is rich in
nutrients, such as polyphenols, amino acids, vitamins, glycosides, and so on. Among them …

Mitochondrial dysfunction and autophagy in hepatic ischemia/reperfusion injury

KL Go, S Lee, I Zendejas, KE Behrns… - BioMed research …, 2015 - Wiley Online Library
Ischemia/reperfusion (I/R) injury remains a major complication of liver resection,
transplantation, and hemorrhagic shock. Although the mechanisms that contribute to hepatic …