T Hozumi, T Kageyama, S Ohta, J Fukuda… - …, 2018 - ACS Publications
We developed an injectable gelatin/hyaluronic acid hydrogel with slow degradability, which consisted of carbohydrazide-modified gelatin (Gel-CDH) and hyaluronic acid monoaldehyde …
Hydrogels have evolved over the last decade as materials of choice in varied biomedical applications. This is associated with the inherent biocompatible nature of the hydrogels. The …
Bone morphogenetic protein-2 (BMP-2) is a potent osteoinductive factor, yet its clinical use is limited by a short biological half-life, rapid local clearance and propensity for side effects …
Injectable hydrogels based on extracellular matrix-derived polymers show much promise in the field of tissue engineering and regenerative medicine. However, the hydrogels reported …
Microstructure plays an essential role in the control of hydrogel properties. It is also an important factor when cells or drugs are encapsulated inside the hydrogel. In this work, the …
BE Larsen, J Bjørnstad, EO Pettersen, HH Tønnesen… - BMC …, 2015 - Springer
Background This work investigates a general method for producing alginate gel matrices using an internal mode of gelation that depends solely on soluble alginate and …
The simplicity and versatility of hydrazone crosslinking has made it a strategy of choice for the conjugation of bioactive molecules. However, the labile nature of hydrazone linkages …
R Ravichandran, MM Islam, EI Alarcon… - Journal of Materials …, 2016 - pubs.rsc.org
In this study, we derivatized type I collagen without altering its triple helical conformation to allow for facile hydrogel formation via the Michael addition of thiols to methacrylates without …
The development of printable hydrogel inks for extrusion-based 3D printing is opening new possibilities to the production of new and/or improved pharmaceutical forms, specifically for …