Ocular allergy remains a significant burden to the population while the treatment for the
severe, chronic forms of allergic conjunctivitis remains largely limited to non-specific …

A series of biological barriers need to be overcome for therapeutic nanocarriers
accumulating at the tumor site and uptaken by cancer cells. One strategy is to construct …

Dry eye disease (DED) is a multifactorial chronic ocular surface inflammatory condition.
Disease severity has been directly related to the immuno-inflammatory status of the ocular …

Importance Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been found to improve
low-grade systemic and tissue inflammation; however, the association between SGLT2 …

Purpose Ocular allergy leads to acute and chronic inflammation that may deteriorate the
conjunctiva and other ocular tissue. The conjunctiva is covered with abundant lymphatic …

Purpose We have demonstrated that deletion of fibroblast growth factor receptor 2 gene
(Fgfr2) leads to Meibomian gland (MG) atrophy in an inducible conditional knockout mouse …

Meibomian gland dysfunction (MGD) is a leading cause of dry eye disease and one of the
most common ophthalmic conditions encountered in eye clinics worldwide. These holocrine …

Purpose: The aim of the study was to examine subjective responses to cyclosporine A (CsA)
0.05% versus lifitegrast 5% in individuals with dry eye disease. Methods: This study was a …

Keratoconus (KC) is a complex multifactorial corneal ectatic disorder, with disease onset
commonly in the second-third decades significantly affecting quantity, quality of vision, and …

Purpose To investigate the role of aggressive meibomian gland dysfunction (MGD) in the
immune pathogenesis of ocular graft-vs-host disease (GVHD). Methods In mice, an …