Response assessment in neuro-oncology (a report of the RANO group): assessment of outcome in trials of diffuse low-grade gliomas

MJ van den Bent, JS Wefel, D Schiff… - The lancet …, 2011 - thelancet.com
Although low-grade gliomas (LGG) have a less aggressive course than do high-grade
gliomas, the outcome of these tumours is ultimately fatal in most patients. Both the tumour …

Diffuse infiltrating oligodendroglioma and astrocytoma

MJ van den Bent, M Smits, JM Kros… - Journal of Clinical …, 2017 - ascopubs.org
The new 2016 WHO brain tumor classification defines different diffuse gliomas primarily
according to the presence or absence of IDH mutations (IDH-mt) and combined 1p/19q loss …

Vorasidenib, a dual inhibitor of mutant IDH1/2, in recurrent or progressive glioma; results of a first-in-human phase I trial

IK Mellinghoff, M Penas-Prado, KB Peters… - Clinical Cancer …, 2021 - AACR
Abstract Purpose: Lower grade gliomas (LGGs) are malignant brain tumors. Current therapy
is associated with short-and long-term toxicity. Progression to higher tumor grade is …

MRI features predict survival and molecular markers in diffuse lower-grade gliomas

H Zhou, M Vallières, HX Bai, C Su, H Tang… - Neuro …, 2017 - academic.oup.com
Background. Previous studies have shown that MR imaging features can be used to predict
survival and molecular profile of glioblastoma. However, no study of a similar type has been …

Spontaneous and therapeutic prognostic factors in adult hemispheric World Health Organization Grade II gliomas: a series of 1097 cases

L Capelle, D Fontaine, E Mandonnet… - Journal of …, 2013 - thejns.org
Object The spontaneous prognostic factors and optimal therapeutic strategy for WHO Grade
II gliomas (GIIGs) have yet to be unanimously defined. Specifically, the role of resection is …

Epileptic seizures in diffuse low-grade gliomas in adults

J Pallud, E Audureau, M Blonski, N Sanai, L Bauchet… - Brain, 2014 - academic.oup.com
Diffuse low-grade gliomas are highly epileptogenic brain tumours. We aimed to explore the
natural course of epileptic seizures, their predictors and the prognostic significance of their …

The T2-FLAIR mismatch sign as an imaging marker for non-enhancing IDH-mutant, 1p/19q-intact lower-grade glioma: a validation study

MPG Broen, M Smits, MMJ Wijnenga… - Neuro …, 2018 - academic.oup.com
Background The purpose of this study was to assess the reproducibility of the previously
described T2–fluid attenuated inversion recovery (FLAIR) mismatch sign as a specific …

Guidelines on management of low‐grade gliomas: report of an EFNS–EANO* Task Force

R Soffietti, BG Baumert, L Bello… - European journal of …, 2010 - Wiley Online Library
Background: Diffuse infiltrative low‐grade gliomas of the cerebral hemispheres in the adult
are a group of tumors with distinct clinical, histological and molecular characteristics, and …

Genomic correlates of disease progression and treatment response in prospectively characterized gliomas

P Jonsson, AL Lin, RJ Young, NM DiStefano… - Clinical Cancer …, 2019 - AACR
Purpose: The genomic landscape of gliomas has been characterized and now contributes to
disease classification, yet the relationship between molecular profile and disease …

IDH-wildtype glioblastomas and grade III/IV IDH-mutant gliomas show elevated tracer uptake in fibroblast activation protein–specific PET/CT

M Röhrich, A Loktev, AK Wefers, A Altmann… - European journal of …, 2019 - Springer
Purpose Targeting fibroblast activation protein (FAP) is a new diagnostic approach allowing
the visualization of tumor stroma. Here, we applied FAP-specific PET imaging to gliomas …