Artificial intelligence in ovarian cancer histopathology: a systematic review

J Breen, K Allen, K Zucker, P Adusumilli… - NPJ Precision …, 2023 - nature.com
This study evaluates the quality of published research using artificial intelligence (AI) for
ovarian cancer diagnosis or prognosis using histopathology data. A systematic search of …

[HTML][HTML] Role of artificial intelligence in digital pathology for gynecological cancers

YL Wang, S Gao, Q Xiao, C Li, M Grzegorzek… - Computational and …, 2024 - Elsevier
The diagnosis of cancer is typically based on histopathological sections or biopsies on glass
slides. Artificial intelligence (AI) approaches have greatly enhanced our ability to extract …

Deep learning artificial intelligence predicts homologous recombination deficiency and platinum response from histologic slides

EN Bergstrom, A Abbasi, M Díaz-Gay… - Journal of Clinical …, 2024 - ascopubs.org
PURPOSE Cancers with homologous recombination deficiency (HRD) can benefit from
platinum salts and poly (ADP-ribose) polymerase inhibitors. Standard diagnostic tests for …

[HTML][HTML] Deep learning for detecting brca mutations in high-grade ovarian cancer based on an innovative tumor segmentation method from whole slide images

R Bourgade, N Rabilloud, T Perennec, T Pécot… - Modern Pathology, 2023 - Elsevier
BRCA1 and BRCA2 genes play a crucial role in repairing DNA double-strand breaks
through homologous recombination. Their mutations represent a significant proportion of …

Deep learning-enabled breast cancer endocrine response determination from H&E staining based on ESR1 signaling activity

CW Ng, KK Wong - Scientific reports, 2023 - nature.com
Estrogen receptor (ER) positivity by immunohistochemistry has long been a main selection
criterium for breast cancer patients to be treated with endocrine therapy. However, ER …

Artificial intelligence to predict the BRAF V595E mutation in canine urinary bladder urothelial carcinomas

L Küchler, C Posthaus, K Jäger, F Guscetti… - Animals, 2023 - mdpi.com
Simple Summary In canine urothelial carcinoma, the BRAF gene is frequently mutated
(V595E). To detect this mutation, urine or tissue samples are currently tested by PCR …

Emerging strategies to overcome PARP inhibitors' resistance in ovarian cancer

R Bi, L Chen, M Huang, Z Qiao, Z Li, G Fan… - Biochimica et Biophysica …, 2024 - Elsevier
The utilization of PARP inhibitors (PARPis) has significantly improved the prognosis for
ovarian cancer patients. However, as the use of PARPis increases, the issue of PARPi …

Biomarkers in high grade serous ovarian cancer

M Bates, BM Mohamed, F Lewis, S O'Toole… - … et Biophysica Acta (BBA …, 2024 - Elsevier
High-grade serous ovarian cancer (HGSC) is the most common subtype of ovarian cancer.
HGSC patients typically present with advanced disease, which is often resistant to …

Computational pathology: an evolving concept

I Prassas, B Clarke, T Youssef, J Phlamon… - Clinical Chemistry and …, 2024 - degruyter.com
The initial enthusiasm about computational pathology (CP) and artificial intelligence (AI) was
that they will replace pathologists entirely on the way to fully automated diagnostics. It is …

Predicting BRCA mutation and stratifying targeted therapy response using multimodal learning: a multicenter study

Y Li, X Xiong, X Liu, M Xu, B Yang, X Li, Y Li… - Annals of …, 2024 - Taylor & Francis
Background The status of BRCA1/2 genes plays a crucial role in the treatment decision-
making process for multiple cancer types. However, due to high costs and limited resources …