Fetal metabolic programming caused by the adverse intrauterine environment can induce
metabolic syndrome in adult offspring. Adverse intrauterine environment introduces fetal …

The prevalence of diabetes in children and adolescents has been rising gradually, which is
relevant to adverse environment during development, especially prepartum. We aimed to …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic
threat with more than 11.8 million confirmed cases and more than 0.5 million deaths as of 3 …

The homeobox transcription factor Nkx6. 1 is sufficient to increase functional β-cell mass,
where functional β-cell mass refers to the combination of β-cell proliferation, glucose …

Background: Sodium valproate (VPA) is an antiepileptic drug (AED) licensed for epilepsy
and used during pregnancy in various indications. Alpha-lipoic acid (ALA) is a natural …

Epilepsy is the chronic non-communicable disease of the nervous system most prevalent in
the world. Valproic acid (VPA) is one of the most used drugs in the treatment of epilepsy but …

Amaç: Bu çalışmanın amacı timokinonun (TQ) valproik asit (VPA) kaynaklı pankreas hasarını
önleme veya tedavi etmedeki potansiyel etkisinin, sıçanların pankreas dokusundaki gen …

Kanker lidah merupakan salah satu kanker terbanyak dengan mortalitas tertinggi di dunia.
Radioterapi dan kemoterapi pada kanker relatif terbatas karena toksisitasnya yang tinggi …

Background: Tongue cancer represents the predominant malignancy within the oral cavity
(25-40% of squamous cell carcinoma), necessitating treatment modalities such as surgery …

Valproat (VPA), antiepileptički lijek/teratogen je također epigenetički inhibitor histonske
deacetilaze (HDACi). Cilj disertacije bio je istražiti aktivnost VPA na gastrulaciju sisavaca u …