Chronic viral infections in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)

S Rasa, Z Nora-Krukle, N Henning, E Eliassen… - Journal of Translational …, 2018 - Springer
Background and main text Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is
a complex and controversial clinical condition without having established causative factors …

Role of infection and neurologic dysfunction in chronic fatigue syndrome

AL Komaroff, TA Cho - Seminars in neurology, 2011 - thieme-connect.com
Chronic fatiguing illnesses following well-documented infections and acute “infectious-like”
illnesses of uncertain cause have been reported for many decades. Chronic fatigue …

The perils of pathogen discovery: origin of a novel parvovirus-like hybrid genome traced to nucleic acid extraction spin columns

SN Naccache, AL Greninger, D Lee, LL Coffey… - Journal of …, 2013 - Am Soc Microbiol
Next-generation sequencing was used for discovery and de novo assembly of a novel,
highly divergent DNA virus at the interface between the Parvoviridae and Circoviridae. The …

Benefit from B-lymphocyte depletion using the anti-CD20 antibody rituximab in chronic fatigue syndrome. A double-blind and placebo-controlled study

Ø Fluge, O Bruland, K Risa, A Storstein… - PloS one, 2011 - journals.plos.org
Background Chronic fatigue syndrome (CFS) is a disease of unknown aetiology. Major CFS
symptom relief during cancer chemotherapy in a patient with synchronous CFS and …

Failure to confirm XMRV/MLVs in the blood of patients with chronic fatigue syndrome: a multi-laboratory study

G Simmons, SA Glynn, AL Komaroff, JA Mikovits… - Science, 2011 - science.org
Murine leukemia viruses (MLVs), including xenotropic-MLV–related virus (XMRV), have
been controversially linked to chronic fatigue syndrome (CFS). To explore this issue in …

Elimination of foreign sequences in eukaryotic viral reference genomes improves the accuracy of virome analysis

J Chen, Y Sun, X Yan, Z Ren, G Wang, Y Liu, Z Zhao… - Msystems, 2022 - Am Soc Microbiol
Widespread in public databases, foreign contaminant sequences pose a substantial
obstacle in genomic analyses. Such contamination in viral genome databases is also …

Integrated tyramide and polymerization-assisted signal amplification for a highly-sensitive immunoassay

L Yuan, L Xu, S Liu - Analytical chemistry, 2012 - ACS Publications
A novel strategy for ultrasensitive detection of model protein based on the integration of
tyramide signal amplification (TSA) and polymerization-assisted signal amplification was …

False Alarm: XMRV, Cancer, and Chronic Fatigue Syndrome

JM Coffin, MF Kearney - Annual Review of Virology, 2024 - annualreviews.org
Xenotropic murine leukemia virus (MLV)-related virus (XMRV) was first described in 2006 in
some human prostate cancers. But it drew little attention until 2009, when it was also found …

Metagenomic identification of viral sequences in laboratory reagents

AF Porter, J Cobbin, CX Li, JS Eden, EC Holmes - Viruses, 2021 - mdpi.com
Metagenomic next-generation sequencing has transformed the discovery and diagnosis of
infectious disease, with the power to characterise the complete 'infectome'(bacteria, viruses …

DNA extraction columns contaminated with murine sequences

O Erlwein, MJ Robinson, S Dustan, J Weber, S Kaye… - PLoS …, 2011 - journals.plos.org
Sequences of the novel gammaretrovirus, xenotropic murine leukemia virus-related virus
(XMRV) have been described in human prostate cancer tissue, although the amounts of …