NMOSD acute attack: Understanding, treatment and innovative treatment prospect

X Ma, AG Kermode, X Hu, W Qiu - Journal of Neuroimmunology, 2020 - Elsevier
Neuromyelitis optica spectrum disorder (NMOSD) is a group of severe inflammatory
demyelinating disorders of the central nervous system that involves the optic nerve and …

Anti-IL-6 therapies for neuromyelitis optica spectrum disorders: a systematic review of safety and efficacy

I Lotan, R McGowan, M Levy - Current Neuropharmacology, 2021 - ingentaconnect.com
Background: Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune
disease of the central nervous system that causes recurrent attacks of optic neuritis, myelitis …

OCT retinal nerve fiber layer thickness differentiates acute optic neuritis from MOG antibody-associated disease and Multiple Sclerosis: RNFL thickening in acute optic …

JJ Chen, ES Sotirchos, AD Henderson… - Multiple sclerosis and …, 2022 - Elsevier
Background Optic neuritis (ON) is the most common manifestation of myelin oligodendrocyte
glycoprotein antibody associated disorder (MOGAD) and multiple sclerosis (MS). Acute ON …

An update on optic neuritis

JA Kraker, JJ Chen - Journal of Neurology, 2023 - Springer
Optic neuritis (ON) is the most common cause of subacute optic neuropathy in young adults.
Although most cases of optic neuritis (ON) are classified as typical, meaning idiopathic or …

CD8+ T cells recognizing a neuron-restricted antigen injure axons in a model of multiple sclerosis

BDS Clarkson, EM Grund… - The Journal of …, 2023 - Am Soc Clin Investig
CD8+ T cells outnumber CD4+ cells in multiple sclerosis (MS) lesions associated with
disease progression, but the pathogenic role and antigenic targets of these clonally …

Recent advances on optic nerve magnetic resonance imaging and post-processing

LS Chow, MNJ Paley - Magnetic Resonance Imaging, 2021 - Elsevier
The optic nerve is known to be one of the largest nerve bundles in the human central
nervous system. There have been many studies of optic nerve imaging and post-processing …

The neuro-ophthalmological manifestations of NMOSD and MOGAD—a comprehensive review

N Moheb, JJ Chen - Eye, 2023 - nature.com
Optic neuritis (ON) is one of the most frequently seen neuro-ophthalmic causes of vision loss
worldwide. Typical ON is often idiopathic or seen in patients with multiple sclerosis, which is …

Inebilizumab reduces neuromyelitis optica spectrum disorder risk independent of FCGR3A polymorphism

HJ Kim, O Aktas, KR Patterson, S Korff… - Annals of Clinical …, 2023 - Wiley Online Library
Inebilizumab, a humanized, glycoengineered, IgG1 monoclonal antibody that depletes
CD19+ B‐cells, is approved to treat aquaporin 4 (AQP4) IgG‐seropositive neuromyelitis …

Visual fields and optical coherence tomography (OCT) in neuro-ophthalmology: structure-function correlation

L Donaldson, E Margolin - Journal of the Neurological Sciences, 2021 - Elsevier
Visual field (VF) testing is an essential component of the neurological examination. The
differential diagnosis of VF defects depends on relating this measure of afferent visual …

[HTML][HTML] Efficacy and safety of inebilizumab in Asian participants with neuromyelitis optica spectrum disorder: Subgroup analyses of the N-MOmentum study

K Fujihara, HJ Kim, T Saida, T Misu, Y Nagano… - Multiple Sclerosis and …, 2023 - Elsevier
Background Inebilizumab, an anti-CD19 B cell-depleting antibody, reduced the risk of a
neuromyelitis optica spectrum disorder (NMOSD) attack, disability worsening, magnetic …