It is not a coincidence that both chirality and noncovalent interactions are ubiquitous in
nature and synthetic molecular systems. Noncovalent interactivity between chiral molecules …

The enantioconvergent cross-coupling of racemic alkyl halides represents a powerful tool for
the synthesis of enantioenriched molecules. In this regard, the first-row transition metal …

In contrast with the well-established enantioconvergent radical C (sp 3)–C cross-coupling of
racemic secondary alkyl electrophiles, the corresponding coupling of tertiary electrophiles to …

The substitution of an alkyl electrophile by a nucleophile is a foundational reaction in
organic chemistry that enables the efficient and convergent synthesis of organic molecules …

Beyond esoteric interest, organocatalysis has now become one major pillar of asymmetric
catalysis. Here, we discuss how new activation modes are conquering challenging …

Halogen bonding, the noncovalent interaction based on electrophilic halogen substituents,
features very interesting properties, as illustrated by numerous applications continuously …

Aliphatic azides are a versatile class of compounds found in a variety of biologically active
pharmaceuticals. These compounds are also recognized as useful precursors for the …

An efficient and general radical hydroamination of alkenes using Co (salen) as catalyst, N‐
fluorobenzenesulfonimide (NFSI) and its analogues as both nitrogen source and oxidant …

Achiral sulfur functional groups, such as sulfonamide, sulfone, thiol and thioether, are
common in drugs and natural products. By contrast, chiral sulfur functional groups are often …

The ability to selectively functionalize ubiquitous C–H bonds streamlines the construction of
complex molecular architectures from easily available precursors. Here we report enzyme …