Structure, biochemical function, and signaling mechanism of plant NLRs

J Wang, W Song, J Chai - Molecular Plant, 2023 - cell.com
To counter pathogen invasion, plants have evolved a large number of immune receptors,
including membrane-resident pattern recognition receptors (PRRs) and intracellular …

Stress-related biomolecular condensates in plants

J Solis-Miranda, M Chodasiewicz, A Skirycz… - The Plant …, 2023 - academic.oup.com
Biomolecular condensates are membraneless organelle-like structures that can concentrate
molecules and often form through liquid-liquid phase separation. Biomolecular condensate …

TIR-catalyzed ADP-ribosylation reactions produce signaling molecules for plant immunity

A Jia, S Huang, W Song, J Wang, Y Meng, Y Sun, L Xu… - Science, 2022 - science.org
Plant pathogen–activated immune signaling by nucleotide-binding leucine-rich repeat
(NLR) receptors with an N-terminal Toll/interleukin-1 receptor (TIR) domain converges on …

TIR domains of plant immune receptors are 2′, 3′-cAMP/cGMP synthetases mediating cell death

D Yu, W Song, EYJ Tan, L Liu, Y Cao, J Jirschitzka, E Li… - Cell, 2022 - cell.com
Summary 2′, 3′-cAMP is a positional isomer of the well-established second messenger
3′, 5′-cAMP, but little is known about the biology of this noncanonical cyclic nucleotide …

Composition and function of stress granules and P-bodies in plants

A Kearly, ADL Nelson, A Skirycz… - Seminars in cell & …, 2024 - Elsevier
Abstract Stress Granules (SGs) and Processing-bodies (P-bodies) are biomolecular
condensates formed in the cell with the highly conserved purpose of maintaining balance …

New biochemical principles for NLR immunity in plants

J Chai, W Song, JE Parker - Molecular Plant-Microbe …, 2023 - Am Phytopath Society
While working for the United States Department of Agriculture on the North Dakota
Agricultural College campus in Fargo, North Dakota, in the 1940s and 1950s, Harold H. Flor …

Plant adenylate cyclases have come full circle

A Wong, W Chi, J Yu, C Bi, X Tian, Y Yang, C Gehring - Nature Plants, 2023 - nature.com
In bacteria, fungi and animals, 3′-5′-cyclic adenosine monophosphate (cAMP) and
adenylate cyclases (ACs), enzymes that catalyse the formation of 3′, 5′-cAMP from ATP …

[HTML][HTML] TIR-catalyzed nucleotide signaling molecules in plant defense

A Jia, S Huang, S Ma, X Chang, Z Han… - Current Opinion in Plant …, 2023 - Elsevier
Toll and interleukin-1 receptor (TIR) domain is a conserved immune module in prokaryotes
and eukaryotes. Signaling regulated by TIR-only proteins or TIR domain-containing …

COLD6-OSM1 module senses chilling for cold tolerance via 2′, 3′-cAMP signaling in rice

W Luo, Y Xu, J Cao, X Guo, J Han, Y Zhang, Y Niu… - Molecular Cell, 2024 - cell.com
While it is known that temperature sensors trigger calcium (Ca 2+) signaling to confer cold
tolerance in cells, less is known about sensors that couple with other secondary …

Landscape of biomolecular condensates in heat stress responses

V Londoño Vélez, F Alquraish, I Tarbiyyah… - Frontiers in Plant …, 2022 - frontiersin.org
High temperature is one of the abiotic stresses that plants face and acts as a major
constraint on crop production and food security. Plants have evolved several mechanisms to …