JN Tants, A Schlundt - Bioscience reports, 2024 - portlandpress.com
Regulatory RNA elements fulfill functions such as translational regulation, control of transcript levels, and regulation of viral genome replication. Trans-acting factors (ie, RNA …
M Shih, Y Zou, T Ferreira, N Suzuki, E Kim… - Plos …, 2024 - journals.plos.org
A recently reported Schizophrenia-associated genetic variant in the 3′ UTR of the human furin gene, a homolog of C. elegans kpc-1, highlights an important role of the furin 3′ UTR …
J Trauth, J Scheffer, S Hasenjäger, C Taxis - Aims Biophysics, 2020 - aimspress.com
In higher eukaryotes, defects in regulated protein turnover are intimately linked to development of diseases and aging. Systematic investigation of proteostasis and protein …
Methylmercury (MeHg) is a well-known neurotoxicant; however, its role in metabolic diseases has been gaining wider attention. We have previously shown that MeHg causes …
RA Malinow, P Ying, T Koorman, M Boxem… - Frontiers in Cellular …, 2019 - frontiersin.org
The basic leucine-zipper (bZIP) domain transcription factors CCAAT/enhancer-binding proteins (C/EBP) have a variety of roles in cell proliferation, differentiation, and stress …
How regulatory sequences control gene expression is fundamental for explaining phenotypes in health and disease. The function of regulatory sequences must ultimately be …
Y Zou, M Shih, H Chiu, T Ferreira, N Suzuki, W Zou… - bioRxiv, 2021 - biorxiv.org
Mechanical stimuli on the skin of C. elegans are detected by the dendritic arbors of PVD nociceptive neurons, which provide uniform sensory coverage outside the head region …