Neurogenesis in Caenorhabditis elegans

RJ Poole, N Flames, L Cochella - Genetics, 2024 - academic.oup.com
Animals rely on their nervous systems to process sensory inputs, integrate these with
internal signals, and produce behavioral outputs. This is enabled by the highly specialized …

The role of structure in regulatory RNA elements

JN Tants, A Schlundt - Bioscience reports, 2024 - portlandpress.com
Regulatory RNA elements fulfill functions such as translational regulation, control of
transcript levels, and regulation of viral genome replication. Trans-acting factors (ie, RNA …

The kpc-1 3′UTR facilitates dendritic transport and translation efficiency of mRNAs for dendrite arborization of a mechanosensory neuron important for male …

M Shih, Y Zou, T Ferreira, N Suzuki, E Kim… - Plos …, 2024 - journals.plos.org
A recently reported Schizophrenia-associated genetic variant in the 3′ UTR of the human
furin gene, a homolog of C. elegans kpc-1, highlights an important role of the furin 3′ UTR …

[HTML][HTML] Strategies to investigate protein turnover with fluorescent protein reporters in eukaryotic organisms

J Trauth, J Scheffer, S Hasenjäger, C Taxis - Aims Biophysics, 2020 - aimspress.com
In higher eukaryotes, defects in regulated protein turnover are intimately linked to
development of diseases and aging. Systematic investigation of proteostasis and protein …

Methylmercury Induces Metabolic Alterations in Caenorhabditis elegans: Role for C/EBP Transcription Factor

SW Caito, J Newell-Caito, M Martell… - Toxicological …, 2020 - academic.oup.com
Methylmercury (MeHg) is a well-known neurotoxicant; however, its role in metabolic
diseases has been gaining wider attention. We have previously shown that MeHg causes …

Functional Dissection of C. elegans bZip-Protein CEBP-1 Reveals Novel Structural Motifs Required for Axon Regeneration and Nuclear Import

RA Malinow, P Ying, T Koorman, M Boxem… - Frontiers in Cellular …, 2019 - frontiersin.org
The basic leucine-zipper (bZIP) domain transcription factors CCAAT/enhancer-binding
proteins (C/EBP) have a variety of roles in cell proliferation, differentiation, and stress …

[图书][B] Parallel genetics of gene regulatory sequences in Caenorhabditis elegans

J Froehlich - 2022 - search.proquest.com
How regulatory sequences control gene expression is fundamental for explaining
phenotypes in health and disease. The function of regulatory sequences must ultimately be …

The kpc-1 (furin) 3'UTR promotes dendritic transport and local translation of mRNAs to regulate dendrite branching and self-avoidance of a nociceptive neuron

Y Zou, M Shih, H Chiu, T Ferreira, N Suzuki, W Zou… - bioRxiv, 2021 - biorxiv.org
Mechanical stimuli on the skin of C. elegans are detected by the dendritic arbors of PVD
nociceptive neurons, which provide uniform sensory coverage outside the head region …