HE4 as a Biomarker for Endometrial Cancer
R Behrouzi, CE Barr, EJ Crosbie - Cancers, 2021 - mdpi.com
Simple Summary There are currently no blood biomarkers approved for routine clinical use
in endometrial cancer. Serum human epididymis protein 4 (HE4) is significantly higher in …
in endometrial cancer. Serum human epididymis protein 4 (HE4) is significantly higher in …
Novel heart failure biomarkers: why do we fail to exploit their potential?
A Piek, W Du, RA de Boer… - Critical reviews in clinical …, 2018 - Taylor & Francis
Plasma biomarkers are useful tools in the diagnosis and prognosis of heart failure (HF). In
the last decade, numerous studies have aimed to identify novel HF biomarkers that would …
the last decade, numerous studies have aimed to identify novel HF biomarkers that would …
Clinical use of cancer biomarkers in epithelial ovarian cancer: updated guidelines from the European Group on Tumor Markers
G Sölétormos, MJ Duffy, SOA Hassan… - International Journal of …, 2016 - ijgc.bmj.com
Objective To present an update of the European Group on Tumor Markers guidelines for
serum markers in epithelial ovarian cancer. Methods Systematic literature survey from 2008 …
serum markers in epithelial ovarian cancer. Methods Systematic literature survey from 2008 …
[HTML][HTML] The emerging role of HE4 in the evaluation of advanced epithelial ovarian and endometrial carcinomas
AR Simmons, K Baggerly, RC Bast Jr - Oncology (Williston Park …, 2013 - ncbi.nlm.nih.gov
Abstract HE4 (human epididymis protein 4) is overexpressed in both ovarian and
endometrial cancers. Levels of the shed HE4 protein are elevated in sera from ovarian and …
endometrial cancers. Levels of the shed HE4 protein are elevated in sera from ovarian and …
HE4 tissue expression and serum HE4 levels in healthy individuals and patients with benign or malignant tumors: a systematic review
NS Karlsen, MA Karlsen, CK Høgdall… - … , Biomarkers & Prevention, 2014 - AACR
Abstract Human epididymis protein 4 (HE4) has received major attention as a potential
tumor marker in epithelial ovarian cancer; however, evidence of significant overexpression …
tumor marker in epithelial ovarian cancer; however, evidence of significant overexpression …
Consideration should be given to smoking, endometriosis, renal function (eGFR) and age when interpreting CA125 and HE4 in ovarian tumor diagnostics
M Lycke, B Ulfenborg… - Clinical Chemistry and …, 2021 - degruyter.com
Objectives To evaluate the impact of different biologic, histopathologic and lifestyle factors
on serum levels of human epididymis protein 4 (HE4) and Cancer antigen 125 (CA125) in …
on serum levels of human epididymis protein 4 (HE4) and Cancer antigen 125 (CA125) in …
The use of HE4, CA125 and CA72-4 biomarkers for differential diagnosis between ovarian endometrioma and epithelial ovarian cancer
E Anastasi, T Granato, R Falzarano, P Storelli… - Journal of ovarian …, 2013 - Springer
Background Endometriosis is frequently associated with high levels of CA125. This marker
is therefore not useful for discriminating ovarian endometrioma from ovarian malignancy …
is therefore not useful for discriminating ovarian endometrioma from ovarian malignancy …
[HTML][HTML] Evaluation of HE4, CA-125, risk of ovarian malignancy algorithm (ROMA) and risk of malignancy index (RMI) in the preoperative assessment of patients with …
K Al Musalhi, M Al Kindi, F Al Aisary… - Oman medical …, 2016 - ncbi.nlm.nih.gov
Objectives To evaluate the validity and compare the performance of cancer antigen-125 (CA-
125), human epididymis protein 4 (HE4), the risk of malignancy index (RMI), and the risk of …
125), human epididymis protein 4 (HE4), the risk of malignancy index (RMI), and the risk of …
The application of circulating tumor cell and cell-free DNA liquid biopsies in ovarian cancer
A Balla, J Bhak, O Biró - Molecular and Cellular Probes, 2022 - Elsevier
Ovarian cancer is the deadliest gynecological cancer. 70% of the cases are diagnosed at
late stages with already developed metastases due to the absence of easily noticeable …
late stages with already developed metastases due to the absence of easily noticeable …
The diagnostic accuracy of human epididymis protein 4 (HE4) for discriminating between benign and malignant pelvic masses: a systematic review and meta‐analysis
M Olsen, P Lof, A Stiekema… - Acta obstetricia et …, 2021 - Wiley Online Library
Introduction Many women with benign pelvic masses, suspected of ovarian cancer, are
unnecessarily referred for treatment at specialized centers. There is an unmet clinical need …
unnecessarily referred for treatment at specialized centers. There is an unmet clinical need …