The chicken embryo model: A novel and relevant model for immune-based studies

P Garcia, Y Wang, J Viallet… - Frontiers in immunology, 2021 - frontiersin.org
Dysregulation of the immune system is associated with many pathologies, including
cardiovascular diseases, diabetes, and cancer. To date, the most commonly used models in …

The New Paradigm in Animal Testing–“3Rs Alternatives”

WT Poh, J Stanslas - Regulatory Toxicology and Pharmacology, 2024 - Elsevier
Regulatory studies have revolutionised over time. Today, the focus has shifted from animal
toxicity testing to non-animal for regulatory safety testing. This move is in line with the …

Polydopamine nanoparticle-based combined chemotherapy and photothermal therapy for the treatment of liver cancer

M Emanet, MC Lefevre, MC Ceccarelli… - … Applied Materials & …, 2024 - ACS Publications
Polydopamine nanoparticles (PDA NPs) are proposed as an anti-cancer tool against
hepatocellular carcinoma through the combination of near-infrared (NIR)-mediated …

[HTML][HTML] PluronicŪ/casein micelles for ophthalmic delivery of resveratrol: In vitro, ex vivo, and in vivo tests

M Vivero-Lopez, C Sparacino… - International Journal of …, 2022 - Elsevier
Ocular health may strongly benefit from the supply of antioxidant agents that counteract free
radicals and reactive oxygen species responsible for long-term eye diseases. Additionally …

The miRNA-21-5p payload in exosomes from M2 macrophages drives tumor cell aggression via PTEN/Akt signaling in renal cell carcinoma

Z Zhang, J Hu, M Ishihara, AC Sharrow, K Flora… - International Journal of …, 2022 - mdpi.com
M2 macrophages in the tumor microenvironment are important drivers of cancer metastasis.
Exosomes play a critical role in the crosstalk between different cells by delivering …

Enhanced Antioxidant, Anti-Aging, Anti-Tyrosinase, and Anti-Inflammatory Properties of Vanda coerulea Griff. Ex Lindl. Protocorm through Elicitations with Chitosan

P Amnuaykan, S Juntrapirom, W Kanjanakawinkul… - Plants, 2024 - mdpi.com
This study aimed to investigate the effects of elicitors on Vanda coerulea Griff. Ex Lindl.
protocorms to enhance bioactive compound production and evaluate their biological …

Antiproliferative Effect of Phellodendron amurense Rupr. Based on Angiogenesis

Ľ Balážová, S Kurhajec, M Kello, Z Bedlovičová… - Life, 2022 - mdpi.com
Phellodendron amurense Rupr. is medicinal plant used for supplemental therapy of various
diseases based on their positive biological activities. The aim of this study was evaluated the …

Technical Implications of the Chicken Embryo Chorioallantoic Membrane Assay to Elucidate Neuroblastoma Biology

CC Patiño-Morales, R Jaime-Cruz… - International Journal of …, 2023 - mdpi.com
The chorioallantoic membrane (CAM) can be used as a valuable research tool to examine
tumors. The CAM can be used to investigate processes such as migration, invasion, and …

[HTML][HTML] Chicken embryo model for in vivo acute toxicological and antitumor efficacy evaluation of lipid nanocarrier containing doxorubicin

ACS Alves, DR Dallemole, TM Ciocheta… - International Journal of …, 2023 - Elsevier
Nanoencapsulation of chemotherapeutics, including doxorubicin, can endow the
formulations with unique properties, such as a decrease in adverse effects and toxicity. The …

[HTML][HTML] Combining antibacterial and wound healing features: Xanthan gum/guar gum 3D-printed scaffold tuned with hydroxypropyl-β-cyclodextrin/thymol and Zn2+

NF Virzì, P Diaz-Rodriguez, A Concheiro, A Otero… - Carbohydrate …, 2025 - Elsevier
Biofilm formation on biological and material surfaces represents a heavy health and
economic burden for both patient and society. To contrast this phenomenon, medical …